CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14231
Family Name Serine/threonine-protein kinase Chk1 inhibitor SureCN4854955 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00427225 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase Chk1 Binder Superfamily 9
Class Class 5035

Cousin Family NamesSeedsMembers
DNA Binder Primaquine Family 3 245
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Hepatocyte growth factor receptor and Vascular endothelial gro... 28 178
Multidrug resistance protein Inhibitor Tariquidar Family 3 60
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor GSK2... 15 18
Vascular endothelial growth factor receptor 2 Ligand E 7080 Fa... 7 17
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Platelet-derived growth factor receptor alpha and Platelet-der... 2 17
Platelet-derived growth factor receptor alpha and Platelet-der... 2 9
Platelet-derived growth factor receptor beta and Epidermal gro... 3 7
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(4-methoxyphenyl)qu... 2 11
Acetylcholinesterase Inhibitor Lysicamine Family 2 8
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
Plasmepsin-2 inhibitor N-[(2S)-1-[[(2S)-6-amino-1-[4-[(6-metho... 5 12
Vascular endothelial growth factor receptor 2 and Aurora kinas... 3 3
Vascular endothelial growth factor receptor 2 ligand AGN-PC-05... 2 2
B2 bradykinin receptor ligand SureCN8516699 family 3 2
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [5-(o... 4 4
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 5 2
Platelet-derived growth factor receptor beta and Receptor-type... 6 5
Platelet-derived growth factor receptor beta and Macrophage co... 1 4
Prostaglandin D2 receptor 2 ligand 2-[1-[4-[(4-methoxybenzoyl)... 2 2
Platelet-derived growth factor receptor alpha and Mast/stem ce... 2 2
Vascular endothelial growth factor receptor 2 and Aurora kinas... 4 3
Hepatocyte growth factor receptor ligand 1-(2-chlorophenyl)-N-... 14 8
Vascular endothelial growth factor receptor 2 ligand N-(4-chlo... 11 7
Mast/stem cell growth factor receptor Kit and Serine/threonine... 11 29
Serine/threonine-protein kinase Chk1 inhibitor 2,3-dimethoxy-9... 15 3
Vascular endothelial growth factor receptor 2 ligand 6-(6,7-di... 4 0
Vascular endothelial growth factor receptor 2 and Cytochrome P... 2 1
Vascular endothelial growth factor receptor 2 ligand N-(4-chlo... 4 4
Vascular endothelial growth factor receptor 2 and Platelet-der... 1 0
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
Vascular endothelial growth factor receptor 2 ligand AGN-PC-00... 9 2
Macrophage colony-stimulating factor 1 receptor ligand 4-(2,3-... 12 7
Macrophage colony-stimulating factor 1 receptor ligand 4-(3-ch... 5 4
Inositol monophosphatase 1 and Prelamin-A/C inhibitor GNF-Pf-3... 1 5
Serine/threonine-protein kinase Chk1 inhibitor 9-(1-methylpyrr... 1 1
Serine/threonine-protein kinase Chk1 inhibitor Chk1_97 family 1 1
Transient receptor potential cation channel subfamily V member... 3 2
Menin and Histone-lysine N-methyltransferase 2A inhibitor CHEM... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00427225 CHEMBL257512 Bioactive SureCN4854955
CFAMM00427224 CHEMBL559498 Bioactive 3-methoxy-9-(3-methoxyphenyl)-2-(pyridin-4-ylmethoxy)-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27074 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543