CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14237
Family Name C-C chemokine receptor type 2 ligand (E)-3-(3,4-dichlorophenyl)-1-[4-[2-hydroxy-1-[4-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]ethyl]piperidin-1-yl]prop-2-en-1-one family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00427243 Functional Category Bioactive
Superfamily C-C chemokine receptor type 2 and Melanin-concentrating hormone receptor 1 Binder Superfamily
Class Class 3170

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A Ligand Melatonin Family 20 988
Cyclooxygenase Inhibitor Indomethacin Family 6 271
Phospholipase A2 Inhibitor Quinacrine Family 13 95
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
D(2) dopamine receptor and D(3) dopamine receptor Ligand L-741... 9 73
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Glycogen synthase kinase-3 beta and Protein kinase C alpha typ... 2 30
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
Kinesin-like protein KIF11 inhibitor AGN-PC-080PZM family 1 11
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 2 10
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 8 21
Somatostatin receptor type 2 ligand tert-butyl (2S)-6-amino-2-... 2 15
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-3-... 8 3
Glucagon receptor and Mitogen-activated protein kinase 14 liga... 6 5
Acetylcholinesterase and Cholinesterase inhibitor N-[5-[(6-chl... 4 2
Proto-oncogene tyrosine-protein kinase receptor Ret and Vascul... 5 14
D(2) dopamine receptor and D(4) dopamine receptor ligand AGN-P... 1 0
C-C chemokine receptor type 2 ligand (E)-1-[4-[2-hydroxy-1-[4-... 2 2
Gamma-aminobutyric acid receptor subunit pi and Gamma-aminobut... 2 10


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00427243 CHEMBL257628 Bioactive (E)-3-(3,4-dichlorophenyl)-1-[4-[2-hydroxy-1-[4-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]ethyl]piperidin-1-yl]prop-2-en-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48707 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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