CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14241
Family Name Neuropeptide Y receptor type 5 ligand 3-[1-(3,5-difluorophenyl)piperidin-4-yl]-1-methyl-1-(1-propylsulfonylpiperidin-4-yl)urea family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00427260 Functional Category Bioactive
Superfamily Neuropeptide Y receptor type 5 and Histamine H3 receptor Binder Superfamily
Class Class 2707

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
5-hydroxytryptamine receptor 1A and Sigma non-opioid intracell... 7 28
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 10
C-C chemokine receptor type 2 and C-C chemokine receptor type ... 2 8
Neuropeptide Y receptor type 5 ligand 3-[1-(3-bromophenyl)pipe... 1 0
Neuropeptide Y receptor type 5 ligand 3-[1-(3,5-dichlorophenyl... 1 0


External ID

Functional Category

Molecule Name

CFAMM00427263 CHEMBL429679 Bioactive 3-[1-(3,5-difluorophenyl)piperidin-4-yl]-1-methyl-1-(1-propan-2-ylsulfonylpiperidin-4-yl)urea
CFAMM00427261 CHEMBL428953 Bioactive 3-[1-(3,5-difluorophenyl)piperidin-4-yl]-1-methyl-1-(1-methylsulfonylpiperidin-4-yl)urea
CFAMM00427260 CHEMBL257708 Bioactive 3-[1-(3,5-difluorophenyl)piperidin-4-yl]-1-methyl-1-(1-propylsulfonylpiperidin-4-yl)urea
CFAMM00427259 CHEMBL257707 Bioactive 3-[1-(3,5-difluorophenyl)piperidin-4-yl]-1-(1-ethylsulfonylpiperidin-4-yl)-1-methylurea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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