CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14244
Family Name Androgen receptor ligand tert-butyl 4-methyl-2,5-dioxo-1H-chromeno[3,4-f]quinoline-10-carboxylate family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00427283 Functional Category Bioactive
Superfamily Androgen receptor Binder Superfamily 8
Class Class 1873

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Tranilast Family 5 125
D(4) dopamine receptor Ligand PD-165167 Family 2 96
Dihydroorotate dehydrogenase and Interleukin-17A Inhibitor Vid... 4 74
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Amine oxidase [flavin-containing] A Inhibitor Ethyl 4-(2-oxo-2... 4 117
Mineralocorticoid receptor and Androgen receptor Ligand AL-43 ... 79 235
Mineralocorticoid receptor and Androgen receptor Ligand LGD-55... 6 6
Amine oxidase [flavin-containing] B Inhibitor N-methyl-n-pheny... 6 25
Beta-ketoacyl-acyl carrier protein synthase III Inhibitor 2-(4... 2 6
Progesterone receptor and Glucocorticoid receptor ligand AGN-P... 6 2
Progesterone receptor and Glucocorticoid receptor ligand (5Z)-... 2 1
Thyroid hormone receptor beta ligand SureCN8800248 family 3 10
Androgen receptor ligand 9-ethoxy-10-methoxy-4-methyl-1H-chrom... 3 4
Androgen receptor ligand trifluoromethyl 10-methoxy-4-methyl-2... 2 57
Androgen receptor ligand 10-(hydroxymethyl)-4-methyl-1,5-dihyd... 2 2
Glucocorticoid receptor and Progesterone receptor ligand SureC... 2 0
Progesterone receptor and Glucocorticoid receptor ligand (5Z)-... 2 2
Progesterone receptor and Androgen receptor ligand (4R,5S)-5-(... 5 0
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN8797384 f... 1 0
Follicle-stimulating hormone receptor ligand (1-acetyl-2,2,4-t... 1 2
Major prion protein and Microtubule-associated protein tau inh... 2 10
methoxybenzoate NP (2-hydroxy-6-methoxyquinolin-3-yl)methyl 4-... 2 1
[3-[(E)-3-(4-methoxyphenyl)-3-oxoprop-1-enyl]phenyl] N,N-diphe... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00427282 CHEMBL258397 Bioactive 9-methoxy-4-methyl-1H-chromeno[3,4-f]quinoline-2,5-dione
CFAMM00427284 CHEMBL257751 Bioactive 10-hydroxy-4-(trifluoromethyl)-1H-isochromeno[3,4-f]quinoline-2,6-dione
CFAMM00427283 CHEMBL401711 Bioactive tert-butyl 4-methyl-2,5-dioxo-1H-chromeno[3,4-f]quinoline-10-carboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27514 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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