CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14252
Family Name Melanin-concentrating hormone receptor 1 and Mu-type opioid receptor ligand 2-[1-[(3R,4R)-1-[[(2S)-5-bromo-2,3-dihydro-1H-inden-2-yl]methyl]-3-methoxypiperidin-4-yl]-5-methylbenzimidazol-2-yl]propan-2-ol family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00427310 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 and Mu-type opioid receptor Binder Superfamily
Class Class 667

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Mizolastine Family 14 603
Melanin-concentrating hormone receptor 1 ligand SureCN3334191 ... 4 7
C-C chemokine receptor type 5 ligand methyl N-cyano-4-[2-[(1R,... 8 8
Histamine H1 receptor and Potassium voltage-gated channel subf... 1 2
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 10 6
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 2 1
Melanin-concentrating hormone receptor 1 ligand (2S)-2-[[(3R,4... 2 0
Small conductance calcium-activated potassium channel protein ... 1 0


External ID

Functional Category

Molecule Name

CFAMM00427310 CHEMBL257906 Bioactive 2-[1-[(3R,4R)-1-[[(2S)-5-bromo-2,3-dihydro-1H-inden-2-yl]methyl]-3-methoxypiperidin-4-yl]-5-methylbenzimidazol-2-yl]propan-2-ol
CFAMM00427309 CHEMBL269939 Bioactive 1-[(3R,4R)-1-[[(2S)-5-bromo-2,3-dihydro-1H-inden-2-yl]methyl]-3-methoxypiperidin-4-yl]-2,5-dimethylbenzimidazole

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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