CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14255
Family Name Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 4-[4-methyl-3-(1-methylindol-4-yl)-1H-1,2,4-triazol-5-ylidene]cyclohexa-2,5-dien-1-one family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00427315 Functional Category Bioactive
Superfamily Delta-type opioid receptor and Mu-type opioid receptor Ligand 1-[3-(4-biphenyl)-(1,2,4-triazol-4-yl) ]-3-phenol Superfamily
Class Class 2343

Cousin Family NamesSeedsMembers
Hepatocyte growth factor receptor Ligand Amg 208 Family 20 236
Tyrosine kinase Inhibitor PKI166 Family 17 198
Glycogen synthase kinase-3 beta and Mitogen-activated protein ... 8 8
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 2 7
Serine/threonine-protein kinase B-raf inhibitor SureCN1015955 ... 17 18
Serine/threonine-protein kinase B-raf inhibitor 3-[7-[4-[[(3R)... 6 7
Serine/threonine-protein kinase Chk2 and Serine/threonine-prot... 3 6
Proto-oncogene tyrosine-protein kinase Src and Tyrosine-protei... 12 8
DNA-(apurinic or apyrimidinic site) lyase and Ras-related prot... 1 5
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 4
Hepatocyte growth factor receptor ligand 4-[(6-phenyl-[1,2,4]t... 3 6
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 2 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 5
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 2
Serine/threonine-protein kinase B-raf inhibitor AGN-PC-07CQG5 ... 2 1
Delta-type opioid receptor and 5-hydroxytryptamine receptor 7 ... 1 6


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00427315 CHEMBL257963 Bioactive 4-[4-methyl-3-(1-methylindol-4-yl)-1H-1,2,4-triazol-5-ylidene]cyclohexa-2,5-dien-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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