CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14256
Family Name Coagulation factor X inhibitor N-(4-chlorophenyl)-2-[[4-(2-oxopyridin-1-yl)benzoyl]amino]benzamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00427316 Functional Category Bioactive
Superfamily Microtubule-associated protein tau and Cytochrome P450 3A4 Binder Superfamily
Class Class 1375

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
5-hydroxytryptamine 2 receptor Ligand Ketanserin Family 10 253
Kinesin-like protein KIF11 Inhibitor Ispinesib Family 4 37
Motilin receptor Ligand GSK962040 Family 30 457
Histone deacetylase 1 Inhibitor AN-9 Family 31 282
K-604 family 4 71
Pan-DAC Inhibitor AR-42 Family 21 153
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
C-C chemokine receptor type 5 Ligand Tak-220 Family 8 56
Vasopressin V2 receptor Ligand FR161282 Family 17 83
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 19 186
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Acetylcholinesterase Inhibitor Bw-28c51 Family 3 8
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 7 35
Cannabinoid receptor 2 Ligand N1-(4-bromophenyl)-n2,n2-dipenty... 4 21
Phospholipase D1 Inhibitor Halopemide Family 17 111
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Metabotropic glutamate receptor 5 Ligand N-(3-acetamidophenyl)... 4 20
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
Sodium-dependent dopamine transporter and Sodium-dependent nor... 19 28
MO15-related protein kinase Pfmrk Inhibitor 2-chloro-n-(o-toly... 6 28
D(2) dopamine receptor Ligand PD-168077 Family 6 5
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
Metabotropic glutamate receptor 5 Ligand 3-cyano-n-(3-cyanophe... 7 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
D(4) dopamine receptor ligand AGN-PC-074VC9 family 2 3
Vasopressin V2 receptor and Vasopressin V1a receptor ligand N-... 5 8
Vasopressin V1a receptor and Vasopressin V2 receptor ligand CH... 3 5
Vasopressin V1a receptor ligand AGN-PC-074VJP family 3 1
Rho-associated protein kinase 2 inhibitor N-(7-chloro-1-oxo-2H... 13 42
Acetylcholinesterase inhibitor AGN-PC-07ZFTY family 1 0
C-C chemokine receptor type 3 ligand 4-[(3-acetylphenyl)carbam... 3 4
Melanocortin receptor 4 and Melanocortin receptor 5 ligand N-[... 16 117
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 4 0
Acetylcholinesterase inhibitor CHEMBL1651130 family 2 3
Vasopressin V2 receptor ligand [2-chloro-4-(prop-2-enylamino)p... 3 14
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 2 4
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 4 3
D(3) dopamine receptor and Alpha-1B adrenergic receptor ligand... 11 8
Cellular tumor antigen p53 and Inositol monophosphatase 1 inhi... 1 12
Prelamin-A/C and Lysine-specific demethylase 4E inhibitor 4-(4... 2 3
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 4 19
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
Ghrelin/growth hormone secretagogue receptor ligand AGN-PC-00A... 7 27
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 8 1
Melanocortin receptor 4 ligand (3R)-N-[(2R)-3-(4-chlorophenyl)... 6 9
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A ... 2 2
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 0
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 5 19
Testosterone 17-beta-dehydrogenase 3 inhibitor AGN-PC-00CHN2 f... 3 2
Melanin-concentrating hormone receptor 1 and Potassium voltage... 2 2
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 11 9
Substance-P receptor and Substance-K receptor ligand AGN-PC-07... 5 2
Cannabinoid receptor 2 ligand AGN-PC-00SRU8 family 1 3
Coagulation factor X and Prothrombin inhibitor SureCN14502287 ... 16 5
Cannabinoid receptor 2 ligand AGN-PC-046LZ0 family 1 0
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
Melanin-concentrating hormone receptor 1 ligand SureCN5517533 ... 2 3
C-C chemokine receptor type 2 ligand 2-amino-N-[2-[[(3R)-1-[(3... 2 4
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 3 2
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 5 1
Sodium-dependent noradrenaline transporter inhibitor AGN-PC-07... 1 1
Histone deacetylase 6 and Histone deacetylase 2 inhibitor 4-[[... 2 1
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 3 3
C-C chemokine receptor type 5 ligand AC1MHPA7 family 2 2
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 3
Cannabinoid receptor 1 ligand SureCN14463736 family 2 0
Vasopressin V2 receptor and Vasopressin V1a receptor ligand (2... 4 0
C-C chemokine receptor type 5 ligand AC1MHP8Y family 1 0
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 4 6
Inositol monophosphatase 1 and Retinal dehydrogenase 1 inhibit... 1 2
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 2
C-X-C chemokine receptor type 3 ligand AGN-PC-00PW0E family 3 11
Acetylcholinesterase and Cholinesterase inhibitor N-[4-[(E)-(6... 1 1
Carbonic anhydrase 9 and Carbonic anhydrase 12 inhibitor 4-oxo... 3 1
C-C chemokine receptor type 2 ligand AGN-PC-00D2HV family 2 2
Vasopressin V1a receptor and Vasopressin V2 receptor ligand Su... 3 0
Glutamate receptor 1 and Glutamate receptor 2 ligand SureCN621... 1 3
Acetylcholinesterase inhibitor 1-(1-benzyl-3,4-dihydro-2H-quin... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00427317 CHEMBL257967 Bioactive N-(3-chlorophenyl)-2-[[4-(2-oxopyridin-1-yl)benzoyl]amino]benzamide
CFAMM00427316 CHEMBL257966 Bioactive N-(4-chlorophenyl)-2-[[4-(2-oxopyridin-1-yl)benzoyl]amino]benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26824 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543