CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14258
Family Name Transient receptor potential cation channel subfamily V member 1 ligand 8-[[6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl]amino]-1,2,3,4-tetrahydronaphthalen-2-ol family
No. of Seeds 5 No. of Other Members 1
Family Centroid CFAMM00427322 Functional Category Bioactive
Superfamily Transient receptor potential cation channel subfamily V member 1 and Hepatocyte growth factor receptor Binder Superfamily
Class Class 3008

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 15 457
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
Mitogen-activated protein kinase 14 and Tyrosine-protein kinas... 3 9
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Mitogen-activated protein kinase 14 inhibitor AGN-PC-03XQYG fa... 7 1
Insulin-like growth factor 1 receptor ligand AGN-PC-09QIDN family 1 3
Transient receptor potential cation channel subfamily V member... 4 0
Growth hormone secretagogue receptor type 1 ligand AGN-PC-0074... 2 3
Tyrosine-protein kinase ITK/TSK and Aurora kinase B inhibitor ... 1 1
Transient receptor potential cation channel subfamily V member... 1 4


External ID

Functional Category

Molecule Name

CFAMM00427320 CHEMBL402637 Bioactive 5-bromo-8-[[6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl]amino]-1,2,3,4-tetrahydronaphthalen-2-ol
CFAMM00427324 CHEMBL258265 Bioactive 7-chloro-8-[[6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl]amino]-1,2,3,4-tetrahydronaphthalen-2-ol
CFAMM00427322 CHEMBL404165 Bioactive 8-[[6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl]amino]-1,2,3,4-tetrahydronaphthalen-2-ol
CFAMM00427321 CHEMBL258056 Bioactive 5-chloro-8-[[6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl]amino]-1,2,3,4-tetrahydronaphthalen-2-ol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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