CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14259
Family Name Disintegrin and metalloproteinase domain-containing protein 17 and Macrophage metalloelastase inhibitor 2-methylbenzofuran, 25 family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00427327 Functional Category Bioactive
Superfamily Histone deacetylase Inhibitor Abexinostat Superfamily
Class Class 216

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Flecainide ... 2 162
C-C chemokine receptor type 5 Ligand GW873140 Family 6 78
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 23
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
5-hydroxytryptamine receptor 1A Ligand Robalzotan Family 9 41
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Histamine H3 receptor Ligand A-349821 Family 49 228
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
D(2) dopamine receptor Ligand Epidepride Family 31 66
D(4) dopamine receptor and D(3) dopamine receptor ligand N-[(3... 2 11
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 2
Renin inhibitor N-[(2S,4S,5S,7S)-7-[2-(1-acetylpiperidin-4-yl)... 2 1
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 2
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 7 18
Nociceptin receptor and Kappa-type opioid receptor ligand AGN-... 1 3
Potassium voltage-gated channel subfamily H member 2 and Melan... 5 4
C-C chemokine receptor type 1 ligand SureCN8184421 family 11 10
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 7 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00427329 CHEMBL402118 Bioactive 2-isopropylbenzofuran, 27
CFAMM00427328 CHEMBL271938 Bioactive 2-isopropylbenzofuran, 28
CFAMM00427327 CHEMBL258055 Bioactive 2-methylbenzofuran, 25
CFAMM00427325 CHEMBL402636 Bioactive 2-methylbenzofuran, 26

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27397 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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