CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14260
Family Name Transient receptor potential cation channel subfamily V member 1 ligand 8-chloro-5-[[6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl]amino]-3,4-dihydro-2H-chromen-3-ol family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00427330 Functional Category Bioactive
Superfamily Epidermal growth factor receptor and Receptor tyrosine-protein kinase erbB-2 Binder Superfamily
Class Class 2955

Cousin Family NamesSeedsMembers
Alpha-1D adrenergic receptor Ligand Terazosin Family 28 638
Peptide deformylase, mitochondrial Inhibitor Trimetrexate Family 4 311
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
Hepatocyte growth factor receptor and Vascular endothelial gro... 28 178
Vascular endothelial growth factor receptor 2 Ligand Cediranib... 8 38
Abelson tyrosine-protein kinase 2 and Proto-oncogene tyrosine-... 25 40
Peptide deformylase, mitochondrial Inhibitor 5-(4-methoxypheno... 5 61
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
Epidermal growth factor receptor Ligand 4-(5-bromoindole-3-yl)... 6 15
Sodium channel protein type 5 subunit alpha Ligand Enecadin Fa... 1 11
Metabotropic glutamate receptor 1 Ligand 4-(cyclohexyloxy)quin... 1 4
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 1 15
3-phosphoinositide-dependent protein kinase 1 and Ribosomal pr... 10 4
Epidermal growth factor receptor ligand N-[4-(3-chloro-4-fluor... 6 47
Cathepsin S and Cathepsin K inhibitor AGN-PC-088VBO family 3 11
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Glucocorticoid receptor ligand (2R)-1,1,1-trifluoro-4-(2-metho... 2 5
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 13
Equilibrative nucleoside transporter 1 inhibitor SureCN9046933... 2 9
Serine/threonine-protein kinase Chk2 and Serine/threonine-prot... 1 0
Fatty-acid amide hydrolase 1 inhibitor (1R)-2-[[6-(3-chloro-4-... 1 4
Dihydrofolate reductase inhibitor 7-(2-ethoxynaphthalen-1-yl)-... 3 2
Proto-oncogene tyrosine-protein kinase Src and Vascular endoth... 7 3
Vascular endothelial growth factor receptor 2 ligand AGN-PC-00... 4 0
Vascular endothelial growth factor receptor 2 ligand AGN-PC-00... 8 1
Receptor tyrosine-protein kinase erbB-2 and Tyrosine-protein k... 1 0
Epidermal growth factor receptor ligand SureCN4454332 family 18 5
Transient receptor potential cation channel subfamily V member... 2 4
Xanthine dehydrogenase/oxidase inhibitor 5-(2-amino-4-oxo-1H-p... 8 30
1-acyl-sn-glycerol-3-phosphate acyltransferase beta inhibitor ... 1 2
Epidermal growth factor receptor ligand 4-Anilinoquinazoline d... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00427330 CHEMBL258117 Bioactive 8-chloro-5-[[6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl]amino]-3,4-dihydro-2H-chromen-3-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27406 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543