CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14268
Family Name Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 3,5-bis(2-chlorophenyl)-4-methyl-1,2,4-triazole family
No. of Seeds 4 No. of Other Members 6
Family Centroid CFAMM00319384 Functional Category Bioactive
Superfamily C-reactive protein Inhibitor ISIS-CRP Superfamily
Class Class 1026

Cousin Family NamesSeedsMembers
C-reactive protein Inhibitor ISIS-CRP Family 4 105
Corticotropin-releasing factor receptor 1 Ligand Dmp-695/696 F... 11 20
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 3 63
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 1 17
Adenosine receptor A2b and Adenosine receptor A2a ligand CP-66... 3 33
Acetylcholinesterase inhibitor [3-(4-chlorophenyl)-5-hexylsulf... 11 16
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL13680... 1 7
Survival motor neuron protein and Nuclear receptor ROR-gamma l... 1 2
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Corticoster... 17 10
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 6 18
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 3 3
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 5-[4-... 1 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Nuclear rec... 9 6
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Corticoster... 2 2
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Corticoster... 4 2
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 4-met... 11 12
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 2 2
Nociceptin receptor and Potassium voltage-gated channel subfam... 10 1
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 1 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 3-[2-... 2 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 3-(2-... 4 3
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor N-met... 2 1
Corticotropin-releasing factor receptor 1 ligand SureCN7215846... 4 1
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 5 1
Corticotropin-releasing factor receptor 1 ligand 4-[7-(dipropy... 1 1
Corticotropin-releasing factor receptor 1 ligand 8-(4-bromo-2-... 1 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 3-[2-... 9 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 17 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 6 0
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-(2-c... 2 0
P2X purinoceptor 7 inhibitor 1-benzyl-5-(2,3-dichlorophenyl)te... 2 6


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00427371 CHEMBL428951 Bioactive 3-(2-chlorophenyl)-4-methyl-5-(4-pentylphenyl)-1,2,4-triazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27525 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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