CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14271
Family Name Cannabinoid receptor 1 ligand AGN-PC-03RV6L family
No. of Seeds 10 No. of Other Members 3
Family Centroid CFAMM00427393 Functional Category Bioactive
Superfamily Myeloperoxidase Inhibitor AZD5904 Superfamily
Class Class 893

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
Multidrug resistance protein Inhibitor Benzquinamide Family 1 41
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Leukotriene B4 receptor 1 Ligand Ltb 019 Family 3 35
Endothelin-1 receptor Ligand Atrasentan Family 127 336
Myeloperoxidase Inhibitor AZD5904 Family 1 2
Substance-P receptor Ligand DA-5018 Family 14 73
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
C-C chemokine receptor type 5 Ligand E-913 Family 6 44
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 3 89
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 8 66
Histamine H3 receptor Ligand A-349821 Family 49 228
Histamine H1 receptor Ligand MDL-105212 Family 16 56
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Neutrophil elastase Inhibitor N,n-bis(cyanomethyl)-3,4-dimetho... 3 30
Intercellular adhesion molecule 1 Inhibitor Dehydropipernonali... 5 36
Urotensin-2 receptor Ligand SB-436811 Family 6 71
DNA topoisomerase 1 Inhibitor NSC-341622 Family 1 1
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 1 2
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
D(2) dopamine receptor Ligand Epidepride Family 31 66
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Pyruvate kinase PKM and Pyruvate kinase PKLR inhibitor MLS0022... 1 0
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Neutrophil elastase inhibitor (2S)-N-[(3S)-6-benzamido-5,5-dif... 6 10
Histamine H3 receptor ligand 1-(3,4-dimethoxyphenyl)-4-(4-pent... 2 0
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 9
Substance-P receptor ligand AGN-PC-075NSQ family 9 3
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL14038... 1 9
Type-2 angiotensin II receptor ligand SureCN244657 family 7 11
Prelamin-A/C and Retinal dehydrogenase 1 inhibitor CHEMBL15810... 1 1
Prelamin-A/C and Beta-lactamase inhibitor CHEMBL1589265 family 1 0
Histamine H1 receptor ligand Ahr 5333 family 1 6
Growth hormone secretagogue receptor type 1 ligand 2-(2-acetyl... 2 0
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 2 3
Orexin receptor type 1 and Orexin receptor type 2 ligand [(2S)... 3 1
Mu-type opioid receptor ligand AGN-PC-075GAW family 2 1
Collagenase 3 and 72 kDa type IV collagenase inhibitor N-[(3,4... 1 6
Prostaglandin D2 receptor 2 and Chemoattractant receptor-homol... 1 1
Melanin-concentrating hormone receptor 1 and Potassium voltage... 12 53
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 15 4
Sodium-dependent noradrenaline transporter and Sodium-dependen... 6 6
Kappa-type opioid receptor and Delta-type opioid receptor liga... 1 3
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 5
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R)-3-(1,3-b... 4 2
Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor ... 2 20
Free fatty acid receptor 1 ligand (3R,4R)-3-[4-(3,4-dimethylph... 4 4
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 2
Muscarinic acetylcholine receptor M3 ligand N-[[3-[3-[(3-methy... 5 2
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07R5XZ family 2 2
Survival motor neuron protein and Muscleblind-like protein 1 i... 1 10
Orexin receptor type 2 and Orexin receptor type 1 ligand 2-ben... 1 0
Prostaglandin D2 receptor ligand (E)-7-[(1S,3S,4R,5R)-4-(1,3-b... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00427396 CHEMBL259656 Bioactive AGN-PC-03RV4M
CFAMM00427389 CHEMBL258753 Bioactive SureCN4467571
CFAMM00427395 CHEMBL259654 Bioactive AGN-PC-03RV6V
CFAMM00427388 CHEMBL408427 Bioactive AGN-PC-00JBHV
CFAMM00427394 CHEMBL258539 Bioactive SureCN3216749
CFAMM00427401 CHEMBL260625 Bioactive SureCN3371264
CFAMM00427393 CHEMBL409472 Bioactive AGN-PC-03RV6L
CFAMM00427400 CHEMBL410339 Bioactive AGN-PC-03RV4W
CFAMM00427391 CHEMBL263391 Bioactive SureCN4468972
CFAMM00427398 CHEMBL409217 Bioactive AGN-PC-03RV7C

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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