CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14273
Family Name Adenosine receptor A2b ligand N-(4-chlorophenyl)-2-[(5Z)-5-(2,6-dioxo-1,3-dipropylpurin-8-ylidene)-3-methyl-1H-pyrazol-2-yl]acetamide family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00427407 Functional Category Bioactive
Superfamily cAMP-specific 3',5'-cyclic phosphodiesterase 4D Inhibitor Arofylline Superfamily
Class Class 1060

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Adenosine receptor A1 and Adenosine receptor A2a Ligand 8-phen... 12 213
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Adenosine receptor A2b Ligand CVT-7124 Family 14 64
RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... 20 90
Adenosine receptor A1 ligand SureCN10614388 family 5 1
Dipeptidyl peptidase 8 and Dipeptidyl peptidase 4 inhibitor Su... 5 13
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
Tyrosine-protein kinase JAK2 inhibitor N-[2-(3-chlorophenyl)-5... 2 11
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QM1E family 8 15
Adenosine receptor A3 and Adenosine receptor A1 ligand (2Z)-2-... 5 3
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 3 13
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206623 family 10 11
DNA gyrase subunit B inhibitor 5-[2-(ethylcarbamoyl)-4-[3-(tri... 2 4
Tyrosine-protein kinase JAK2 inhibitor N-[3-(3-chlorophenyl)-1... 12 4
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 17 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 6
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-fluoro... 5 1
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-chloro... 2 0
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 12 3
Adenosine receptor A2b ligand N-[(3Z)-3-(2,6-dioxo-1,3-dipropy... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00427407 CHEMBL258571 Bioactive N-(4-chlorophenyl)-2-[(5Z)-5-(2,6-dioxo-1,3-dipropylpurin-8-ylidene)-3-methyl-1H-pyrazol-2-yl]acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27291 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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