CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14277
Family Name Macrophage colony-stimulating factor 1 receptor ligand 5-cyano-N-[2-(4-methylpiperidin-1-yl)-4-pyridin-4-ylphenyl]furan-2-carboxamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00427442 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 3A and Neuronal acetylcholine receptor subunit alpha-7 Ligand PH-709829 Superfamily
Class Class 918

Cousin Family NamesSeedsMembers
Cathepsin K Inhibitor Relacatib Family 26 32
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Neuronal acetylcholine receptor subunit alpha-4 Ligand TC-5619... 3 61
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 12 197
Mu-type opioid receptor Ligand 6-(4-(2-(benzylamino)ethyl)phen... 3 27
5-hydroxytryptamine receptor 3A and Neuronal acetylcholine rec... 1 3
Macrophage migration inhibitory factor Inhibitor Benzofuran-2-... 5 67
Collagenase 3 inhibitor N-[[3-[5-[[(1R)-1-cyclohexyl-2-(methyl... 6 9
Collagenase 3 inhibitor N-[[3-[5-[[(1R)-1-cyclohexyl-2-(methyl... 4 2
Cathepsin S and Cathepsin K inhibitor N-[(2S)-3-(1-methylcyclo... 2 0
Cytochrome P450 2C19 and Inositol monophosphatase 1 inhibitor ... 1 0
Histamine H3 receptor ligand SureCN2784306 family 5 3
Serine/threonine-protein kinase B-raf inhibitor furan-based co... 6 3
MAP kinase-activated protein kinase 2 inhibitor 5-(4-cyanophen... 3 8
MAP kinase-activated protein kinase 2 inhibitor 4-[5-[[2-(2-me... 3 4
MAP kinase-activated protein kinase 2 inhibitor 4-[4-oxo-8-pip... 4 0
Macrophage colony-stimulating factor 1 receptor ligand SureCN1... 6 1
Macrophage colony-stimulating factor 1 receptor ligand 5-cyano... 5 6
Cathepsin K and Cathepsin L1 inhibitor AC1NR9VX family 2 2
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-073HN6 f... 1 1
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 3-(2,3-... 2 1
Collagenase 3 inhibitor SureCN1316041 family 4 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00427442 CHEMBL258709 Bioactive 5-cyano-N-[2-(4-methylpiperidin-1-yl)-4-pyridin-4-ylphenyl]furan-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27698 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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