CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14278
Family Name Nociceptin receptor and Mu-type opioid receptor ligand SureCN12195150 family
No. of Seeds 11 No. of Other Members 14
Family Centroid CFAMM00427460 Functional Category Bioactive
Superfamily Nociceptin receptor and Mu-type opioid receptor Binder Superfamily 10
Class Class 178

Cousin Family NamesSeedsMembers
Methionine aminopeptidase 2 Inhibitor 2-(pyridin-2-yl)-1h-benz... 6 19
Nociceptin receptor ligand 6-fluoro-2-pentan-3-ylsulfanyl-5-pi... 1 4
Nociceptin receptor ligand 2-[(2,3-dichlorophenyl)methylsulfan... 1 1
Nociceptin receptor ligand benzimidazole analogue, 7g family 9 1
Nociceptin receptor and Potassium voltage-gated channel subfam... 2 0


External ID

Functional Category

Molecule Name

CFAMM00427450 CHEMBL263919 Bioactive 2-[4-[6-chloro-2-(2-methylbutan-2-ylsulfanyl)-1H-benzimidazol-5-yl]piperazin-1-yl]ethanol
CFAMM00427449 CHEMBL263918 Bioactive AGN-PC-04SQG3
CFAMM00427461 CHEMBL263903 Bioactive 6-chloro-5-(4-ethylpiperazin-1-yl)-2-pentan-3-ylsulfanyl-1H-benzimidazole
CFAMM00427447 CHEMBL407325 Bioactive SureCN6485013
CFAMM00427460 CHEMBL494350 Bioactive SureCN12195150
CFAMM00427453 CHEMBL495402 Bioactive 2-[(3S)-4-(2-tert-butylsulfanyl-6-chloro-1H-benzimidazol-5-yl)-3-methylpiperazin-1-yl]ethanol
CFAMM00427466 CHEMBL466630 Bioactive benzimidazole analogue, 5e
CFAMM00427446 CHEMBL468504 Bioactive benzimidazole analogue, 5a
CFAMM00427465 CHEMBL258710 Bioactive 6-chloro-2-pentan-3-ylsulfanyl-5-piperazin-1-yl-1H-benzimidazole
CFAMM00427451 CHEMBL263917 Bioactive 2-[4-[6-chloro-2-(1-methylcyclohexyl)sulfanyl-1H-benzimidazol-5-yl]piperazin-1-yl]ethanol
CFAMM00427464 CHEMBL494219 Bioactive AGN-PC-077JUX

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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