CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14283
Family Name Cysteinyl leukotriene receptor 1 ligand 1-[[4-[(2-chlorophenyl)sulfonylcarbamoyl]-2-methoxyphenyl]methyl]-3-methyl-N-(4,4,4-trifluoro-2-methylbutyl)indole-6-carboxamide family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00427486 Functional Category Bioactive
Superfamily Cysteinyl leukotriene receptor 1 Ligand Zafirlukast Superfamily
Class Class 82

Cousin Family NamesSeedsMembers
Cysteinyl leukotriene receptor 1 Ligand Zafirlukast Family 48 78
Cyclooxygenase Inhibitor Indomethacin Family 6 271
Glycogen synthase kinase-3 beta and Protein kinase C alpha typ... 2 30
Peroxisome proliferator-activated receptor gamma ligand NSI fa... 5 3
Endothelin-1 receptor and Endothelin B receptor ligand AGN-PC-... 11 10
Prostaglandin E2 receptor EP3 subtype ligand (E)-N-(3,4-difluo... 3 3


External ID

Functional Category

Molecule Name

CFAMM00427489 CHEMBL25885 Bioactive 3-[[4-[(2-chlorophenyl)sulfonylcarbamoyl]-2-methoxyphenyl]methyl]-1-methyl-N-(4,4,4-trifluoro-2-methylbutyl)indole-5-carboxamide
CFAMM00427488 CHEMBL285300 Bioactive 1-[[4-[(2-chlorophenyl)sulfonylcarbamoyl]-2-methoxyphenyl]methyl]-N-(4,4,4-trifluoro-2-methylbutyl)indole-6-carboxamide
CFAMM00427487 CHEMBL26002 Bioactive 3-[[4-[(2-bromophenyl)sulfonylcarbamoyl]-2-methoxyphenyl]methyl]-N-(2-ethyl-4,4,4-trifluorobutyl)-1-methylindole-5-carboxamide
CFAMM00427486 CHEMBL284128 Bioactive 1-[[4-[(2-chlorophenyl)sulfonylcarbamoyl]-2-methoxyphenyl]methyl]-3-methyl-N-(4,4,4-trifluoro-2-methylbutyl)indole-6-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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