CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14295
Family Name Adenosine receptor A1 and Adenosine receptor A2a ligand N-[4-(1,3-benzodioxol-5-yl)-5-cyano-6-phenylpyrimidin-2-yl]cyclopentanecarboxamide family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00377854 Functional Category Bioactive
Superfamily Adenosine receptor A1 and Adenosine receptor A3 Binder Superfamily 7
Class Class 377

Cousin Family NamesSeedsMembers
Alpha-1D adrenergic receptor Ligand Terazosin Family 28 638
Peptide deformylase, mitochondrial Inhibitor Trimetrexate Family 4 311
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
Vascular endothelial growth factor receptor 2 Ligand Cediranib... 8 38
Tyrosine kinase Inhibitor PKI166 Family 17 198
Peptide deformylase, mitochondrial Inhibitor 8-(2,3,4-trimetho... 8 15
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
TGF-beta receptor type-1 Ligand SB-431542 Family 2 42
Epidermal growth factor receptor Ligand 4-(5-bromoindole-3-yl)... 6 15
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 1 15
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 5 45
Survival motor neuron protein inhibitor CHEMBL1307497 family 1 2
Dual specificity protein kinase CLK1 and Dual specificity prot... 2 14
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 8 12
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL13704... 1 7
Dual specificity tyrosine-phosphorylation-regulated kinase 1A ... 3 20
Prostaglandin D2 receptor ligand 2-[3-[2-methoxy-6-[2-(4-metho... 4 12
Prostaglandin D2 receptor ligand 1-[3-[2-methoxy-6-[2-(4-metho... 6 16
Adenosine receptor A3 ligand AGN-PC-08WSLM family 5 22
Adenosine receptor A1 and Adenosine receptor A3 ligand AGN-PC-... 6 8
Dihydrofolate reductase inhibitor 7-(3,4-dimethoxyphenyl)-6-me... 1 3
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 2
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-amin... 4 3
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Adenosine receptor A2a ligand AGN-PC-077RYH family 16 5
Adenosine receptor A1 ligand BAS 00727702 family 1 4
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 1 1
Dual specificity protein kinase CLK4 and Dual specificity tyro... 6 2
TGF-beta receptor type-1 ligand AGN-PC-07CRDB family 5 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00427572 CHEMBL260396 Bioactive N-[6-(1,3-benzodioxol-5-yl)-5-cyano-2-phenylpyrimidin-4-yl]cyclopentanecarboxamide
CFAMM00427571 CHEMBL261088 Bioactive N-[4-(1,3-benzodioxol-5-yl)-6-phenylpyrimidin-2-yl]cyclopentanecarboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27036 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543