CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14298
Family Name Nociceptin receptor ligand 6-fluoro-2-pentan-3-ylsulfanyl-5-piperazin-1-yl-1H-benzimidazole family
No. of Seeds 1 No. of Other Members 4
Family Centroid CFAMM00427580 Functional Category Bioactive
Superfamily Nociceptin receptor Binder Superfamily 2
Class Class 178

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Mizolastine Family 14 603
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Methionine aminopeptidase 2 Inhibitor 2-(pyridin-2-yl)-1h-benz... 6 19
Mitogen-activated protein kinase 14 and Tyrosine-protein kinas... 1 9
Sterol O-acyltransferase 1 inhibitor 1-(2,4-difluorophenyl)-3-... 8 90
Methionine aminopeptidase 2 inhibitor SureCN5373581 family 6 0
Nociceptin receptor and Mu-type opioid receptor ligand SureCN1... 11 14
Nociceptin receptor ligand 2-[(2,3-dichlorophenyl)methylsulfan... 1 1
Nociceptin receptor ligand benzimidazole analogue, 7g family 9 1
Nociceptin receptor and Potassium voltage-gated channel subfam... 2 0
Sodium/hydrogen exchanger 1 inhibitor 2-[(E)-[2-(1H-benzimidaz... 3 14
Sterol O-acyltransferase 1 inhibitor SureCN9370585 family 1 0


External ID

Functional Category

Molecule Name

CFAMM00427580 CHEMBL259452 Bioactive 6-fluoro-2-pentan-3-ylsulfanyl-5-piperazin-1-yl-1H-benzimidazole

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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