CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14303
Family Name Mitogen-activated protein kinase 8 inhibitor 4-[(6-chloro-1-oxo-4-phenyl-3-propanoylisoquinolin-2-yl)methyl]-N,2-dimethylimidazole-1-carboxamide family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00427601 Functional Category Bioactive
Superfamily Substance-K receptor and Substance-P receptor Binder Superfamily 3
Class Class 3183

Cousin Family NamesSeedsMembers
Farnesyltransferase beta subunit, putative Inhibitor Zarnestra... 10 56
Farnesyltransferase beta subunit, putative and Protein farnesy... 20 81
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 9 3
Coagulation factor X and Prothrombin inhibitor 2-carboxyindole... 2 8
Sodium- and chloride-dependent glycine transporter 1 and Sodiu... 4 8
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075X3N ... 1 7
Substance-K receptor ligand SureCN9035669 family 10 5
Thromboxane-A synthase inhibitor 6-chloro-3-(4-imidazol-1-ylbu... 12 21
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 2 0
Substance-K receptor ligand AGN-PC-074GCM family 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00427601 CHEMBL259484 Bioactive 4-[(6-chloro-1-oxo-4-phenyl-3-propanoylisoquinolin-2-yl)methyl]-N,2-dimethylimidazole-1-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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