CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14311
Family Name Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-3 beta inhibitor 6-aryl-pyrazolo[3,4-b]pyridine analogue 5 family
No. of Seeds 7 No. of Other Members 6
Family Centroid CFAMM00392772 Functional Category Bioactive with Natural Product
Superfamily Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3 alpha Binder Superfamily 2
Class Class 3176

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 29 421
Cyclin-dependent kinase 2 and Mitogen-activated protein kinase... 7 30
Epidermal growth factor receptor and Tyrosine-protein kinase A... 4 3
Tyrosine-protein kinase HCK and Proto-oncogene tyrosine-protei... 5 9
Proto-oncogene tyrosine-protein kinase Src and Tyrosine-protei... 12 8
Translocator protein inhibitor AGN-PC-080ILF family 9 3
Adenosine receptor A2a ligand AGN-PC-077RWY family 4 5
Prothrombin and Survival motor neuron protein inhibitor CHEMBL... 2 14
Tyrosine-protein kinase JAK2 inhibitor 5-(3-methoxyphenyl)-N-[... 2 11
Adenosine receptor A3 ligand AGN-PC-08WSLM family 5 22
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 1 6
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 6 0
Adenosine receptor A1 and Adenosine receptor A2a ligand AGN-PC... 4 2
Tyrosine-protein kinase JAK2 inhibitor N-(3-methylphenyl)-5-(3... 2 4
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 4 4
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 4 1
Adenosine receptor A2a ligand AGN-PC-077RYH family 16 5
Adenosine receptor A2a ligand AGN-PC-077RYF family 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00427653 CHEMBL260662 Bioactive AC1O6ZUO
CFAMM00427659 CHEMBL408019 Bioactive AC1O6ZUA
CFAMM00427650 CHEMBL260345 Bioactive 6-aryl-pyrazolo[3,4-b]pyridine analogue 7
CFAMM00427655 CHEMBL260664 Bioactive AC1O6ZUM
CFAMM00427654 CHEMBL259838 Bioactive pyrazolo[3,4-b]pyridine analogue 7

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26839 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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