CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14320
Family Name Progesterone receptor ligand (8S,11R,13S,14S,16R,17S)-17-(cyclopropanecarbonyl)-11-[4-(6-methoxypyridin-3-yl)phenyl]-13,16-dimethyl-2,6,7,8,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-one family
No. of Seeds 5 No. of Other Members 1
Family Centroid CFAMM00427702 Functional Category Bioactive
Superfamily Sodium-dependent serotonin transporter and Transporter Binder Superfamily 5
Class Class 1002

Cousin Family NamesSeedsMembers
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 22 57
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase inhibit... 2 24


External ID

Functional Category

Molecule Name

CFAMM00427703 CHEMBL407371 Bioactive (8S,11R,13S,14S,16S,17S)-17-(cyclopropanecarbonyl)-16-ethenyl-11-[4-(6-methoxypyridin-3-yl)phenyl]-13-methyl-2,6,7,8,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-one
CFAMM00427702 CHEMBL260869 Bioactive (8S,11R,13S,14S,16R,17S)-17-(cyclopropanecarbonyl)-11-[4-(6-methoxypyridin-3-yl)phenyl]-13,16-dimethyl-2,6,7,8,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-one
CFAMM00427701 CHEMBL260330 Bioactive (8S,11R,13S,14S)-11-[4-(6-methoxypyridin-3-yl)phenyl]-13-methylspiro[1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-17,2'-cyclopentane]-1',3-dione
CFAMM00427699 CHEMBL411522 Bioactive (8S,11R,13S,14S,17S)-17-(cyclopropanecarbonyl)-11-[4-(6-methoxypyridin-3-yl)phenyl]-13-methyl-2,6,7,8,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-one
CFAMM00427704 CHEMBL406439 Bioactive (8S,11R,13S,14S,16R,17S)-17-(cyclopropanecarbonyl)-16-ethyl-11-[4-(6-methoxypyridin-3-yl)phenyl]-13-methyl-2,6,7,8,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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