CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14337
Family Name Putative Bioactive 5-hexyl-2-[4-[(4-methylpiperazin-1-yl)methyl]phenoxy]phenol Family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00427748 Functional Category Bioactive
Superfamily Acetylcholinesterase Inhibitor Galantamine Superfamily
Class Class 332

Cousin Family NamesSeedsMembers
Voltage-dependent T-type calcium channel subunit alpha-1I liga... 5 209
Noradrenergic re-uptake and Serotonin re-uptake inhibitor bicy... 6 375
u-type opioid receptor ligand opiate analog Buprenorphine Family 78 234
Nicotinic acetylcholine receptor alpha subunit Ligand benzylis... 4 18
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
D(1B) dopamine receptor Ligand Apomorphine Family 30 271
Neuronal acetylcholine receptor subunit alpha-2 Ligand Metocur... 18 169
Muscarinic acetylcholine receptor M3 Ligand Tolterodine Family 8 171
Beta adrenergic receptor Ligand Dipivefrin Family 3 55
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Alpha adrenergic receptor Ligand Bevantolol Family 4 48
Glaziovine family 1 4
D(3) dopamine receptor Ligand U-99194A Family 7 33
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Vernakalant family 1 1
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Arachidonate 5-lipoxygenase Inhibitor Bw A360C Family 12 8
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
M-phase inducer phosphatase 1 Inhibitor Naphthoquinone Analogs... 11 56
Peptide deformylase, mitochondrial Inhibitor Tylophorinidine F... 7 1
Tumor necrosis factor Inhibitor Y-39041 Family 9 51
Histamine H3 receptor Ligand A-331440 Family 6 7
Histamine H3 receptor Ligand UCL-2138 Family 23 172
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 25 50
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Sodium-dependent noradrenaline transporter Inhibitor WAY-25680... 4 6
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Tubulin beta chain Inhibitor Colchinol Family 3 109
D(2) dopamine receptor and Sodium-dependent dopamine transport... 6 10
D(2) dopamine receptor and D(1A) dopamine receptor Ligand 3-ch... 2 0
Sodium-dependent dopamine transporter Inhibitor Secocularidine... 3 9
5-hydroxytryptamine receptor 1A ligand SureCN7035190 family 10 17
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 7 0
D(1A) dopamine receptor ligand DOXANTHINE family 3 0
D(1A) dopamine receptor and D(3) dopamine receptor ligand N,N-... 3 1
Transient receptor potential cation channel subfamily V member... 14 7
Sigma non-opioid intracellular receptor 1 ligand BAS 04057753 ... 5 8
Histamine H3 receptor and Sodium-dependent serotonin transport... 15 1
Carbonic anhydrase 7 and Carbonic anhydrase 14 inhibitor 4-(6-... 7 8
7-dehydrocholesterol reductase inhibitor 2-[2-(4-chlorophenyl)... 2 3
Dipeptidyl peptidase 4 inhibitor SureCN8267584 family 1 1
Histamine H3 receptor and Sodium-dependent serotonin transport... 6 1
Sodium-dependent serotonin transporter and Histamine H3 recept... 7 0
Transient receptor potential cation channel subfamily V member... 4 40
Alpha-2A adrenergic receptor and Alpha-2C adrenergic receptor ... 2 26


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00427748 CHEMBL261355 Bioactive 5-hexyl-2-[4-[(4-methylpiperazin-1-yl)methyl]phenoxy]phenol
CFAMM00427746 CHEMBL408149 Bioactive 5-hexyl-2-[2-[(4-methylpiperazin-1-yl)methyl]phenoxy]phenol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26380 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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