CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14347
Family Name Type-1 angiotensin II receptor and Type-2 angiotensin II receptor ligand EMD-66684 family
No. of Seeds 35 No. of Other Members 14
Family Centroid CFAMM00427797 Functional Category Bioactive
Superfamily Type-1 angiotensin II receptor and Type-2 angiotensin II receptor Binder Superfamily 7
Class Class 3528

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Losartan Family 3 90
Type-1 angiotensin II receptor Ligand Candesartan Family 3 75
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Type-1 angiotensin II receptor Ligand Olmesartan Family 13 65
Type-1 angiotensin II receptor Ligand Tasosartan Family 10 29
Adenosine receptor A2a Ligand (e,e)-8-(4-phenylbutadien-1-yl)c... 11 43
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
Type-2 angiotensin II receptor Ligand SC-50560 Family 3 84
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SCH-577... 9 29
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 16 30
C-X-C chemokine receptor type 4 and Envelope glycoprotein gp16... 2 2
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 4 4
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 27
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 6
Type-1B angiotensin II receptor ligand SureCN683399 family 3 0
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 7 9
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL14574... 1 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 9 6
Type-1 angiotensin II receptor and Peroxisome proliferator-act... 6 0
Type-1 angiotensin II receptor ligand 7-methyl-N-(2-phenylethy... 2 10
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 5
Type-1 angiotensin II receptor and Type-1A angiotensin II rece... 8 0
Type-1 angiotensin II receptor and Peroxisome proliferator-act... 3 16
Type-1 angiotensin II receptor ligand 5-[2-[4-[[4-butyl-3-[[4-... 4 2
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 4 3
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 8 2
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 1 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 1 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 2 0
Type-1B angiotensin II receptor and Type-1 angiotensin II rece... 1 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 9 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 2 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 4
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 5 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 5 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 1 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 8 1
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 5
Type-1 angiotensin II receptor ligand 2-[(2-ethyl-5,7-dimethyl... 5 3
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 1 0
Glucagon receptor ligand SureCN2666184 family 7 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00427792 CHEMBL295854 Bioactive 2-(2-butyl-4-oxo-3-{[2'-(2h-tetrazol-5-yl)biphenyl-4-yl]methyl}-3,4-dihydro-5h-imidazo[4,5-c]pyridin-5-yl)-n,n-diethylacetamide
CFAMM00427805 CHEMBL298417 Bioactive N-tert-butyl-2-[2-butyl-4-oxo-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazo[4,5-c]pyridin-5-yl]acetamide
CFAMM00427785 CHEMBL290248 Bioactive 2-[2-butyl-4-oxo-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazo[4,5-c]pyridin-5-yl]-N-methyl-N-phenylacetamide
CFAMM00427811 CHEMBL289291 Bioactive SureCN9583456
CFAMM00427804 CHEMBL43171 Bioactive 2-butyl-5-[(2-chlorophenyl)methyl]-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazo[4,5-c]pyridin-4-one
CFAMM00427817 CHEMBL42184 Bioactive 2-[2-butyl-4-oxo-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazo[4,5-c]pyridin-5-yl]-N-phenylacetamide
CFAMM00427797 CHEMBL288246 Bioactive EMD-66684
CFAMM00427803 CHEMBL42397 Bioactive SureCN8081233
CFAMM00427816 CHEMBL43424 Bioactive AGN-PC-00FJC8
CFAMM00427809 CHEMBL44925 Bioactive 2-butyl-5-[(2-fluorophenyl)methyl]-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazo[4,5-c]pyridin-4-one
CFAMM00427822 CHEMBL418625 Bioactive N,N-diethyl-2-[2-ethyl-4-oxo-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazo[4,5-c]pyridin-5-yl]acetamide
CFAMM00427815 CHEMBL43500 Bioactive AGN-PC-00FIBG
CFAMM00427795 CHEMBL430570 Bioactive 5-[(2-bromophenyl)methyl]-2-butyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazo[4,5-c]pyridin-4-one
CFAMM00427808 CHEMBL298464 Bioactive 2-butyl-5-ethyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazo[4,5-c]pyridin-4-one
CFAMM00427821 CHEMBL295966 Bioactive 2-butyl-5-phenacyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazo[4,5-c]pyridin-4-one
CFAMM00427788 CHEMBL42287 Bioactive 2-butyl-5-[(4-chlorophenyl)methyl]-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazo[4,5-c]pyridin-4-one
CFAMM00427801 CHEMBL295456 Bioactive 2-butyl-5-methyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazo[4,5-c]pyridin-4-one
CFAMM00427814 CHEMBL47187 Bioactive SureCN8080801
CFAMM00427807 CHEMBL291043 Bioactive 2-[2-ethyl-4-oxo-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazo[4,5-c]pyridin-5-yl]-N,N-dimethylacetamide
CFAMM00427820 CHEMBL43535 Bioactive AGN-PC-073O9H
CFAMM00427787 CHEMBL296472 Bioactive 2-butyl-5-[(2-nitrophenyl)methyl]-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazo[4,5-c]pyridin-4-one
CFAMM00427800 CHEMBL295929 Bioactive 2-butyl-5-[(3-chlorophenyl)methyl]-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazo[4,5-c]pyridin-4-one
CFAMM00427813 CHEMBL42775 Bioactive N,N-dimethyl-2-[4-oxo-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazo[4,5-c]pyridin-5-yl]acetamide
CFAMM00427786 CHEMBL297358 Bioactive 2-[2-butyl-4-oxo-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazo[4,5-c]pyridin-5-yl]acetamide
CFAMM00427799 CHEMBL295928 Bioactive 2-[2-cyclopropyl-4-oxo-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazo[4,5-c]pyridin-5-yl]-N,N-dimethylacetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26391 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543