CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1435
Family Name 5-hydroxytryptamine receptor 6 ligand AGN-PC-03P3TZ family
No. of Seeds 6 No. of Other Members 88
Family Centroid CFAMM00323394 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 6 and High affinity cAMP-specific Binder Superfamily
Class Class 1154

Cousin Family NamesSeedsMembers
PF-3758309 family 1 8
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-chlo... 11 20
Prostaglandin G/H synthase 2 Inhibitor GW-637185X Family 27 48
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 22
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Aurora kinase B and Aurora kinase A inhibitor AGN-PC-07ZBLC fa... 3 8
Cellular tumor antigen p53 inhibitor F3165-0515 family 2 12
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 13 100
5-hydroxytryptamine receptor 6 ligand AGN-PC-0BIUF2 family 25 11
5-hydroxytryptamine receptor 6 ligand F1609-0206 family 2 6
5-hydroxytryptamine receptor 6 ligand AGN-PC-031XQS family 1 1
Histamine H4 receptor ligand 2-[[6-iodo-2-(4-methylpiperazin-1... 4 2
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 3 10
Growth hormone secretagogue receptor type 1 and Dihydrofolate ... 3 6
Cell division cycle 7-related protein kinase inhibitor AGN-PC-... 6 6
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 5 27
Corticotropin-releasing factor receptor 1 ligand N-butyl-N-eth... 2 1
Fatty-acid amide hydrolase 1 inhibitor 5-[5-(4-chlorophenyl)su... 2 4
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 7 21
TGF-beta receptor type-1 ligand 6-[(5E)-5-(4-methyl-3H-1,3-thi... 22 9
TGF-beta receptor type-1 and Mitogen-activated protein kinase ... 6 4
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 7
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 3 6
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 2 1
Prostaglandin G/H synthase 2 inhibitor 4-N,4-N-diethyl-2-(4-me... 5 1
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 2
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... 4 5
Histamine H4 receptor and Histamine H1 receptor ligand 6-chlor... 1 0
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 4
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 3


External ID

Functional Category

Molecule Name

CFAMM00323442 CHEMBL1173578 Bioactive AGN-PC-00RIYX
CFAMM00323394 CHEMBL1173211 Bioactive AGN-PC-03P3TZ
CFAMM00323407 CHEMBL1170673 Bioactive CHEMBL1170673
CFAMM00323361 CHEMBL1170672 Bioactive AGN-PC-031XQU
CFAMM00323367 CHEMBL1172726 Bioactive AGN-PC-00RJ6D
CFAMM00323427 CHEMBL1169707 Bioactive AGN-PC-00RJ6H

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



113707 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543