CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14350
Family Name Proto-oncogene tyrosine-protein kinase Src and Tyrosine-protein kinase BTK inhibitor SureCN6621670 family
No. of Seeds 8 No. of Other Members 21
Family Centroid CFAMM00427886 Functional Category Bioactive
Superfamily GABA theta subunit and DNA polymerase beta Binder Superfamily
Class Class 3178

Cousin Family NamesSeedsMembers
Coagulation factor VII inhibitor [3-[(5E)-5-(5-carbamimidoyl-1... 3 2
Serine/threonine-protein kinase Chk1 inhibitor 6-chloro-3-(1,3... 4 2
Tyrosine-protein kinase Lck inhibitor 6,7-dimethyl-2-(2,4,6-tr... 1 0


External ID

Functional Category

Molecule Name

CFAMM00427889 CHEMBL27485 Bioactive 2-(2,6-dichloroanilino)-7-[(E)-2-hydroxyethenyl]-1,6-dimethyl-8H-imidazo[4,5-h]isoquinolin-9-one
CFAMM00427869 CHEMBL424220 Bioactive SureCN6623007
CFAMM00427888 CHEMBL27350 Bioactive SureCN6622152
CFAMM00427868 CHEMBL26214 Bioactive 7-[(E)-3-[benzyl(methyl)amino]prop-1-enyl]-2-(2,6-dichloroanilino)-1,6-dimethyl-8H-imidazo[4,5-h]isoquinolin-9-one
CFAMM00427886 CHEMBL281957 Bioactive SureCN6621670
CFAMM00427866 CHEMBL432089 Bioactive SureCN6621073
CFAMM00427878 CHEMBL30230 Bioactive SureCN6622139
CFAMM00427871 CHEMBL287175 Bioactive SureCN6845488

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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