CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14351
Family Name Gonadotropin-releasing hormone receptor ligand (3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamidobutanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-4-[[(3S,6S,9R,12R)-3-[(2R)-2-[[(2S)-1-amino-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]-9-[3-(diaminomethylideneamino)propyl]-6-(2-methylpropyl)-5,8,11,15-tetraoxo-4,7,10,16-tetrazabicyclo[15.2.2]henicosa-1(19),17,20-trien-12-yl]amino]-4-oxobutanoic acid family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00427893 Functional Category Bioactive
Superfamily Gonadotropin-releasing hormone Inhibitor ASP3550 Superfamily
Class Class 980

Cousin Family NamesSeedsMembers
Gastrin/cholecystokinin type B receptor ligand peptide Pentaga... 26 1171
Somatostatin receptor type 2 ligand octapeptide Octreotide Family 27 172
Bacterial outer membrane Inhibitor Daptomycin Family 6 50
Substance-P receptor Ligand GSK424887 Family 8 184
Growth hormone receptor Ligand EP-51216 Family 34 390
ABC294640 family 5 75
Gonadotropin-releasing hormone Inhibitor ASP3550 Family 33 60
Cholecystokinin receptor type A Ligand A-71378 Family 77 23
Gastrin/cholecystokinin type B receptor Ligand PD136450 Family 53 117
Lethal factor Inhibitor GM6001 Family 50 435
Gonadotropin-releasing hormone receptor Ligand Azaline B Family 12 0
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[n... 12 10
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Gonadotropin-releasing hormone receptor Ligand [d-ncy(methyl)4... 32 0
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[c... 20 18
Endothelin B receptor Ligand IRL-2500 Family 34 87
Vasopressin V1a receptor and Vasopressin V1b receptor Ligand D... 10 19
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
Gonadotropin-releasing hormone receptor ligand (3S)-3-[[(2R)-2... 1 0
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 1
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 2 2
Growth factor receptor-bound protein 2 ligand [4-[(2S)-2-aceta... 5 2
KiSS-1 receptor ligand SureCN5132924 family 2 4
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00427894 CHEMBL385090 Bioactive (3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamidobutanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-4-[[(3S,6S,9R,12R)-3-[(2R)-2-[[(2S)-1-amino-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]-6-(2-methylpropyl)-5,8,11,14-tetraoxo-9-(pyridin-3-ylmethyl)-4,7,10,15-tetrazabicyclo[14.2.2]icosa-1(18),16,19-trien-12-yl]amino]-4-oxobutanoic acid
CFAMM00427893 CHEMBL412681 Bioactive (3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamidobutanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-4-[[(3S,6S,9R,12R)-3-[(2R)-2-[[(2S)-1-amino-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]-9-[3-(diaminomethylideneamino)propyl]-6-(2-methylpropyl)-5,8,11,15-tetraoxo-4,7,10,16-tetrazabicyclo[15.2.2]henicosa-1(19),17,20-trien-12-yl]amino]-4-oxobutanoic acid
CFAMM00427892 CHEMBL440436 Bioactive 3-[(3S,6R,9S,12R,15R,20R)-15-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamidobutanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-(4-aminobutyl)-18-(2-amino-2-oxoethyl)-9-[3-(diaminomethylideneamino)propyl]-6-(2-methylpropyl)-2,5,8,11,14,17,19-heptaoxo-1,4,7,10,13,18-hexazabicyclo[18.3.0]tricosan-12-yl]propanoic acid
CFAMM00427891 CHEMBL265169 Bioactive (3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamidobutanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-4-[[(3S,6S,9R,12R)-3-[(2R)-2-[[(2S)-1-amino-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]-6-(2-methylpropyl)-5,8,11,15-tetraoxo-9-(pyridin-3-ylmethyl)-4,7,10,16-tetrazabicyclo[15.2.2]henicosa-1(19),17,20-trien-12-yl]amino]-4-oxobutanoic acid
CFAMM00427890 CHEMBL262160 Bioactive (3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamidobutanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-4-[[(2R,5S,8S,20R)-8-[(2R)-2-[[(2S)-1-amino-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]-2-[3-(diaminomethylideneamino)propyl]-5-(2-methylpropyl)-3,6,11,13,17,21-hexaoxo-1,4,7,12,16-pentazacyclohenicos-20-yl]amino]-4-oxobutanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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