CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14358
Family Name Pol polyprotein inhibitor 183854-98-0 family
No. of Seeds 15 No. of Other Members 2
Family Centroid CFAMM00427930 Functional Category Bioactive
Superfamily Pol polyprotein and Mitogen-activated protein kinase 8 Binder Superfamily
Class Class 4797

Cousin Family NamesSeedsMembers
HIV protease Inhibitor Indinavir Family 36 211
HIV-1 protease Inhibitor Atazanavir Family 16 58
Pol polyprotein inhibitor AC1LAD48 family 19 5
Pol polyprotein inhibitor N-[3-[[(4R,5R,6R)-4-benzyl-5-hydroxy... 1 0
Renin inhibitor (3R)-4-[[(2S,5S)-1-cyclohexyl-3-hydroxy-6-meth... 3 4
Pol polyprotein inhibitor Cyclic Urea 68 family 4 0
Pol polyprotein inhibitor 183854-15-1 family 3 0


External ID

Functional Category

Molecule Name

CFAMM00427927 CHEMBL431027 Bioactive 183856-54-4
CFAMM00427917 CHEMBL316407 Bioactive 3-[[(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-3-(3-nitrophenyl)-2-oxo-1,3-diazepan-1-yl]methyl]-N-pyridin-2-ylbenzamide
CFAMM00427923 CHEMBL85990 Bioactive 183854-99-1
CFAMM00427926 CHEMBL286672 Bioactive Tetrahydropyrimidinone deriv. 73
CFAMM00427925 CHEMBL434427 Bioactive AC1LAFWN
CFAMM00427915 CHEMBL85585 Bioactive 183855-01-8
CFAMM00427931 CHEMBL315825 Bioactive 183856-69-1
CFAMM00427921 CHEMBL431017 Bioactive 183854-16-2
CFAMM00427924 CHEMBL314058 Bioactive 183856-56-6
CFAMM00427930 CHEMBL85653 Bioactive 183854-98-0
CFAMM00427920 CHEMBL81383 Bioactive AC1LAFVQ
CFAMM00427929 CHEMBL262378 Bioactive 183854-97-9
CFAMM00427919 CHEMBL434612 Bioactive AC1LAFWK
CFAMM00427928 CHEMBL408834 Bioactive 183855-10-9
CFAMM00427918 CHEMBL313357 Bioactive 3-[[(4R,5S,6S,7R)-3-(3-aminophenyl)-4,7-dibenzyl-5,6-dihydroxy-2-oxo-1,3-diazepan-1-yl]methyl]-N-(5-methylpyridin-2-yl)benzamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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