CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14360
Family Name Cysteinyl leukotriene receptor 1 ligand 2-[1-[[(1R)-1-[3-[(E)-2-(5-fluoro-1,3-benzothiazol-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetic acid family
No. of Seeds 6 No. of Other Members 2
Family Centroid CFAMM00427952 Functional Category Bioactive
Superfamily Cysteinyl leukotriene receptor 1 Ligand Montelukast Superfamily
Class Class 215

Cousin Family NamesSeedsMembers
Cysteinyl leukotriene receptor 1 Ligand Montelukast Family 37 29
Prostaglandin D2 receptor 2 Ligand 2-(2-benzhydryl-4-phenylthi... 14 61
Squalene synthase inhibitor SureCN7761201 family 2 14
Prostaglandin D2 receptor 2 ligand AGN-PC-0143RG family 6 13
Prostaglandin D2 receptor 2 ligand AGN-PC-00DDG8 family 3 25
Cysteinyl leukotriene receptor 1 and Cysteinyl leukotriene rec... 7 0
Prostaglandin D2 receptor 2 ligand SureCN5318360 family 4 1
Cysteinyl leukotriene receptor 1 ligand 2-[1-[[(1R)-3-[2-(2-hy... 10 2
Aldose reductase inhibitor AGN-PC-03B8PV family 4 2
Cysteinyl leukotriene receptor 2 and Cysteinyl leukotriene rec... 11 2


External ID

Functional Category

Molecule Name

CFAMM00427949 CHEMBL262391 Bioactive 2-[1-[[(1R)-1-[3-[(E)-2-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetic acid
CFAMM00427948 CHEMBL42520 Bioactive 2-[1-[[(1R)-3-[2-(2-hydroxypropan-2-yl)phenyl]-1-[3-[(E)-2-(4-phenyl-1,3-thiazol-2-yl)ethenyl]phenyl]propyl]sulfanylmethyl]cyclopropyl]acetic acid
CFAMM00427947 CHEMBL39077 Bioactive 2-[1-[[(1R)-1-[3-[(E)-2-(5-chloro-1,3-benzothiazol-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetic acid
CFAMM00427946 CHEMBL41395 Bioactive 2-[1-[[(1R)-3-[2-(2-hydroxypropan-2-yl)phenyl]-1-[3-[(E)-2-[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]ethenyl]phenyl]propyl]sulfanylmethyl]cyclopropyl]acetic acid
CFAMM00427952 CHEMBL43509 Bioactive 2-[1-[[(1R)-1-[3-[(E)-2-(5-fluoro-1,3-benzothiazol-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetic acid
CFAMM00427951 CHEMBL42051 Bioactive 2-[1-[[(1R)-1-[3-[(E)-2-(5,6-difluoro-1,3-benzothiazol-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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