CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14364
Family Name Adenosine receptor A1 and Adenosine receptor A2b ligand (2R,3R,4S,5S)-2-[6-[[(1S)-3-bicyclo[2.2.1]heptanyl]amino]purin-9-yl]-5-(chloromethyl)oxolane-3,4-diol family
No. of Seeds 9 No. of Other Members 0
Family Centroid CFAMM00427974 Functional Category Bioactive
Superfamily Adenosine receptor A1 and Adenosine receptor A2b Binder Superfamily 6
Class Class 172

Cousin Family NamesSeedsMembers
Adenosine receptor A3 ligand purine nucleoside Adenosine Family 47 847
DNA Binder purine nucleoside Adenosine analog Nelarabine Family 2 10
Adenosine receptor A2a Ligand Atl-146e Family 33 94
P2Y purinoceptor 12 Inhibitor Ar-c69931 Mx Family 10 18
Histamine N-methyltransferase Inhibitor S-adenosyl-l-homocyste... 2 3
cAMP-dependent protein kinase type I-alpha regulatory subunit ... 12 0
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 16 6
Adenosine receptor A3 and Adenosine receptor A1 ligand (1R,2R,... 10 15
Adenosine receptor A1 ligand CHEMBL2112106 family 7 7
Adenosine receptor A1 and Adenosine receptor A2a ligand (1S,3S... 3 0
Adenosine receptor A1 ligand CHEMBL258759 family 2 3
Adenosine receptor A2a and Adenosine receptor A2b ligand Cgs-2... 1 2
Adenosine receptor A1 ligand CHEMBL411245 family 1 0
Adenosine receptor A2a and Adenosine receptor A2b ligand 3-[6-... 1 0
Adenosine receptor A2a and Adenosine receptor A2b ligand (3R,4... 7 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00427973 CHEMBL3038259 Bioactive (2R,3R,4S,5S)-2-[6-[[(1R,3R,4S)-3-bicyclo[2.2.1]heptanyl]amino]purin-9-yl]-5-(chloromethyl)oxolane-3,4-diol
CFAMM00427972 CHEMBL262604 Bioactive (2R,3R,4S,5S)-2-[6-[[(1S,3S,4S)-3-bicyclo[2.2.1]heptanyl]amino]purin-9-yl]-5-(fluoromethyl)oxolane-3,4-diol
CFAMM00427971 CHEMBL449575 Bioactive SureCN10608131
CFAMM00427970 CHEMBL3038260 Bioactive (2R,3R,4S,5S)-2-[6-[[(1S,3S)-3-bicyclo[2.2.1]heptanyl]amino]purin-9-yl]-5-(chloromethyl)oxolane-3,4-diol
CFAMM00427969 CHEMBL427737 Bioactive (2R,3R,4S,5S)-2-[6-[[(1S,3S,4S)-3-bicyclo[2.2.1]heptanyl]amino]purin-9-yl]-5-(chloromethyl)oxolane-3,4-diol
CFAMM00427975 CHEMBL477665 Bioactive (2R,3R,4R,5S)-2-[6-(3-bicyclo[2.2.1]heptanylamino)purin-9-yl]-5-(chloromethyl)-3-methyloxolane-3,4-diol
CFAMM00427968 CHEMBL514701 Bioactive (2R,3R,4R,5S)-2-[6-(3-bicyclo[2.2.1]heptanylamino)-2-chloropurin-9-yl]-5-(chloromethyl)-3-methyloxolane-3,4-diol
CFAMM00427974 CHEMBL3038256 Bioactive (2R,3R,4S,5S)-2-[6-[[(1S)-3-bicyclo[2.2.1]heptanyl]amino]purin-9-yl]-5-(chloromethyl)oxolane-3,4-diol
CFAMM00427967 CHEMBL514541 Bioactive (2R,3R,4S,5S)-2-[6-(3-bicyclo[2.2.1]heptanylamino)-2-chloropurin-9-yl]-5-(chloromethyl)oxolane-3,4-diol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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