CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14373
Family Name Arachidonate 5-lipoxygenase inhibitor (E)-3-(3,4-dihydroxyphenyl)-1-[4-(dimethylamino)phenyl]prop-2-en-1-one family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00428033 Functional Category Bioactive
Superfamily Tyrosinase Binder Superfamily 4
Class Class 54

Cousin Family NamesSeedsMembers
Catechol O-methyltransferase Inhibitor Tolcapone Family 7 19
Tyrosinase Inhibitor 4'-amino-4-hydroxychalcone Family 1 4
Benzene and Substituted Derivatives Metabolite N-Acetyl-3-hydr... 1 2


External ID

Functional Category

Molecule Name

CFAMM00428034 CHEMBL339788 Bioactive (E)-3-(3,4-dihydroxyphenyl)-1-[3-(dimethylamino)phenyl]prop-2-en-1-one
CFAMM00428033 CHEMBL262892 Bioactive (E)-3-(3,4-dihydroxyphenyl)-1-[4-(dimethylamino)phenyl]prop-2-en-1-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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