CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14381
Family Name Scytalone dehydratase inhibitor (1R)-2,2-dichloro-1-ethyl-N-[(2R)-1-(4-fluorophenoxy)propan-2-yl]-3-methylcyclopropane-1-carboxamide family
No. of Seeds 9 No. of Other Members 1
Family Centroid CFAMM00428080 Functional Category Bioactive
Superfamily Scytalone dehydratase and Cannabinoid receptor 1 Binder Superfamily
Class Class 412

Cousin Family NamesSeedsMembers
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand (5Z,8... 4 2
Scytalone dehydratase inhibitor (2R)-2-cyano-N-[(2R)-1-(2,3-di... 15 0
Scytalone dehydratase inhibitor 2-cyano-N-[(1S,2R)-1-(2-cyanop... 5 0


External ID

Functional Category

Molecule Name

CFAMM00428086 CHEMBL85505 Bioactive 3-chloro-N-[(2R)-1-(2-fluorophenoxy)propan-2-yl]-3-methyl-1-(trifluoromethyl)cyclobutane-1-carboxamide
CFAMM00428079 CHEMBL295108 Bioactive (1R)-2,2-dichloro-N-[(2R)-1-(2,3-difluorophenoxy)propan-2-yl]-1-ethyl-3-methylcyclopropane-1-carboxamide
CFAMM00428087 CHEMBL41569 Bioactive (1R)-2,2-dichloro-1-ethyl-3-methyl-N-(2-phenoxyethyl)cyclopropane-1-carboxamide
CFAMM00428085 CHEMBL41320 Bioactive (1R)-2,2-dichloro-1-ethyl-3-methyl-N-(1-phenoxypropan-2-yl)cyclopropane-1-carboxamide
CFAMM00428078 CHEMBL298018 Bioactive (1R)-2,2-dichloro-1-ethyl-3-methyl-N-[(2R)-1-phenoxypropan-2-yl]cyclopropane-1-carboxamide
CFAMM00428084 CHEMBL296638 Bioactive (1R)-2,2-dichloro-N-[(2R)-1-(2,5-difluorophenoxy)propan-2-yl]-1-ethyl-3-methylcyclopropane-1-carboxamide
CFAMM00428083 CHEMBL43445 Bioactive (1R)-2,2-dichloro-1-ethyl-N-[(2R)-1-(3-fluorophenoxy)propan-2-yl]-3-methylcyclopropane-1-carboxamide
CFAMM00428082 CHEMBL288484 Bioactive (1R)-2,2-dichloro-1-ethyl-N-[(2R)-1-(2-fluorophenoxy)propan-2-yl]-3-methylcyclopropane-1-carboxamide
CFAMM00428080 CHEMBL263419 Bioactive (1R)-2,2-dichloro-1-ethyl-N-[(2R)-1-(4-fluorophenoxy)propan-2-yl]-3-methylcyclopropane-1-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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