CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14385
Family Name 5-hydroxytryptamine receptor 1A ligand SureCN10513645 family
No. of Seeds 9 No. of Other Members 1
Family Centroid CFAMM00428106 Functional Category Bioactive
Superfamily cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 4-(2,5-diphenyl-furan-3-yl)-morpholine Superfamily
Class Class 1685

Cousin Family NamesSeedsMembers
Mucosal addressin cell adhesion molecule 1 Inhibitor PF-005476... 64 96
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
Sodium channel protein type 10 subunit alpha Ligand A-803467 F... 2 81
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 4-(2... 4 31
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 6 23
Alpha-1A adrenergic receptor Ligand RWJ-68141 Family 5 4
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Leukotriene A-4 hydrolase Inhibitor N5-[4-(2-oxo-3-phenylpropo... 1 61
Macrophage migration inhibitory factor Inhibitor Benzofuran-2-... 5 67
Sodium channel protein type 10 subunit alpha and Sodium channe... 2 13
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 2 17
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 0
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 20 9
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 11 4
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 1
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 4 2
MAP kinase-activated protein kinase 2 inhibitor 5-(4-cyanophen... 3 8
Cathepsin S and Cathepsin K inhibitor arylaminoethyl amide, 7 ... 2 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 1
Translocator protein inhibitor N-[(2,5-dimethoxyphenyl)methyl]... 1 0
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 4 6
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 1 5
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Mu-type opioid receptor ligand AGN-PC-00NCMO family 3 1
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 1 1
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 1 0
Neuropeptide Y receptor type 5 ligand 3-dibenzofuran-2-yl-1-[(... 1 2
Cyclin-dependent kinase 4 inhibitor SureCN3563106 family 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00428100 CHEMBL27655 Bioactive 1-(1-benzofuran-7-yl)-4-(cyclohexylmethyl)piperazine
CFAMM00428106 CHEMBL26834 Bioactive SureCN10513645
CFAMM00428099 CHEMBL27558 Bioactive AGN-PC-0034EN
CFAMM00428098 CHEMBL26355 Bioactive AGN-PC-0034EO
CFAMM00428104 CHEMBL280825 Bioactive AGN-PC-0034EM
CFAMM00428103 CHEMBL26988 Bioactive AGN-PC-0034ET
CFAMM00428102 CHEMBL286287 Bioactive SureCN10514753
CFAMM00428101 CHEMBL96595 Bioactive 1-(1-benzofuran-7-yl)-4-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)piperazine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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