CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14388
Family Name Thyroid hormone receptor alpha and Thyroid hormone receptor beta ligand 5-[[4-(4-hydroxy-3-propan-2-ylphenoxy)-3,5-diiodophenyl]methyl]imidazolidine-2,4-dione family
No. of Seeds 3 No. of Other Members 5
Family Centroid CFAMM00428114 Functional Category Bioactive
Superfamily Thyroid hormone receptor beta and Thyroid hormone receptor alpha Binder Superfamily 10
Class Class 65

Cousin Family NamesSeedsMembers
Thyroid hormone receptor alpha ligand thyroid hormone analog L... 10 61
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 8 14
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 8 1


External ID

Functional Category

Molecule Name

CFAMM00428114 CHEMBL263630 Bioactive 5-[[4-(4-hydroxy-3-propan-2-ylphenoxy)-3,5-diiodophenyl]methyl]imidazolidine-2,4-dione
CFAMM00428112 CHEMBL264153 Bioactive 5-[[4-(3-ethyl-4-hydroxyphenoxy)-3,5-diiodophenyl]methyl]imidazolidine-2,4-dione

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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