CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14390
Family Name Substance-P receptor ligand SureCN8415737 family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00428126 Functional Category Bioactive
Superfamily Substance-P receptor and Muscarinic acetylcholine receptor M3 Binder Superfamily
Class Class 100

Cousin Family NamesSeedsMembers
Opioid receptor ligand synthetic opioid methadone analog Dextr... 2 108
Histamine H1 receptor Ligand Diphenhydramine Family 5 75
Alpha-1B adrenergic receptor ligand Morpholine derivative Phen... 4 152
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Nicotinic acetylcholine receptor Ligand Benztropine Mesylate F... 10 20
Muscarinic acetylcholine receptor Ligand Umeclidinium Family 7 50
Substance-P receptor Ligand L-733060 Family 19 71
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Substance-P receptor Ligand SCH-388714 Family 26 8
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 3 1
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 5 14
5-hydroxytryptamine receptor 7 Ligand (r)-8-phenyl-n,n-dipropy... 9 14
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 9 7
Sodium-dependent dopamine transporter and Sodium-dependent nor... 5 2
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 0
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 2 11
Sigma non-opioid intracellular receptor 1 ligand 2-[(3R)-1'-(c... 2 0
Substance-P receptor ligand (2S)-3-[[3,5-bis(trifluoromethyl)p... 1 4
Substance-P receptor ligand 4-[[3,5-bis(trifluoromethyl)phenyl... 2 1
Substance-P receptor ligand AGN-PC-02K8FR family 1 3
Sodium-dependent dopamine transporter and Sodium-dependent ser... 6 0
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 11 2
Muscarinic acetylcholine receptor M3 ligand 3-[8-methyl-8-(2-p... 3 0
Substance-P receptor ligand 1-[[(1R,2R,3S)-3-[[3,5-bis(trifluo... 4 3
Sodium-dependent dopamine transporter and Transporter inhibito... 2 0
Substance-P receptor ligand AGN-PC-03NGZP family 3 0
Substance-P receptor ligand (1R,2S,3S)-3-[(1R)-1-[3,5-bis(trif... 8 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 0
Sodium-dependent serotonin transporter and Sodium-dependent do... 3 0
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 3 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 3
Sodium-dependent dopamine transporter and Transporter inhibito... 2 0
Substance-P receptor ligand AGN-PC-02K8GG family 1 1
Sodium-dependent dopamine transporter and Sigma non-opioid int... 2 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 0
Substance-P receptor ligand SureCN8912140 family 2 12
Cannabinoid receptor 2 ligand SureCN4472215 family 2 0
Substance-P receptor and Voltage-dependent L-type calcium chan... 1 0
Histamine H1 receptor and 5-hydroxytryptamine receptor 2A liga... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand (4aR,... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00428126 CHEMBL359206 Bioactive SureCN8415737
CFAMM00428124 CHEMBL263795 Bioactive AGN-PC-02K8FK
CFAMM00428127 CHEMBL341863 Bioactive AGN-PC-02K8GQ

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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