CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14391
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 2-cycloheptyl-4-[4-methoxy-3-(5-phenylpentoxy)phenyl]-4a,5,8,8a-tetrahydrophthalazin-1-one family
No. of Seeds 8 No. of Other Members 4
Family Centroid CFAMM00428135 Functional Category Bioactive
Superfamily cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-specific 3',5'-cyclic phosphodiesterase 4D Binder Superfamily
Class Class 928

Cousin Family NamesSeedsMembers
Irdabisant family 49 53
cAMP-specific 3',5'-cyclic phosphodiesterase 4B Inhibitor Fila... 9 9
cAMP-specific 3',5'-cyclic phosphodiesterase 4D Inhibitor Zard... 2 3
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 3 1
Histamine H3 receptor ligand 2-methyl-4-[4-(3-pyrrolidin-1-ylp... 4 1
Histamine H3 receptor ligand 3-methyl-1-[4-(3-piperidin-1-ylpr... 6 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 7 13
Beta-2 adrenergic receptor and cAMP-specific 3',5'-cyclic phos... 4 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 3 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 1 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and Sodium-dep... 2 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4D inhibitor (4aS... 10 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00428132 CHEMBL84657 Bioactive 4-[4-[5-(3-cycloheptyl-4-oxo-4a,5,8,8a-tetrahydrophthalazin-1-yl)-2-methoxyphenoxy]butoxy]benzonitrile
CFAMM00428131 CHEMBL263811 Bioactive AGN-PC-0BODFC
CFAMM00428130 CHEMBL84689 Bioactive 2-cycloheptyl-4-[4-methoxy-3-(6-phenoxyhexoxy)phenyl]-4a,5,8,8a-tetrahydrophthalazin-1-one
CFAMM00428136 CHEMBL315762 Bioactive AGN-PC-04SERG
CFAMM00428129 CHEMBL421347 Bioactive AGN-PC-0BQUS5
CFAMM00428135 CHEMBL310143 Bioactive 2-cycloheptyl-4-[4-methoxy-3-(5-phenylpentoxy)phenyl]-4a,5,8,8a-tetrahydrophthalazin-1-one
CFAMM00428134 CHEMBL315453 Bioactive 2-cycloheptyl-4-[3-(2-hydroxyethoxy)-4-methoxyphenyl]-4a,5,8,8a-tetrahydrophthalazin-1-one
CFAMM00428133 CHEMBL84556 Bioactive AGN-PC-04SERF

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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