CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM144
Family Name Thromboxane A2 receptor and Thromboxane-A synthase ligand AGN-PC-074TM9 family
No. of Seeds 4 No. of Other Members 19
Family Centroid CFAMM00143252 Functional Category Bioactive
Superfamily Thromboxane A2 receptor and Potassium-competitive acid Binder Superfamily
Class Class 8

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B ligand triptan Almotriptan Family 8 438
Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family 8 328
Thromboxane A2 receptor Ligand Bibv 308 Family 14 40
Thromboxane A2 receptor Ligand Ramatroban Family 13 49
Prostaglandin D2 receptor 2 Ligand AZD1981 Family 11 28
Potassium-competitive acid Inhibitor TAK-438 Family 2 8
Thromboxane-A synthase Inhibitor CGS-22652 Family 37 95
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor Quinol... 4 13
Endothelin B receptor Ligand IRL-2500 Family 34 87
Thromboxane-A synthase and Thromboxane A2 receptor ligand (E)-... 2 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 3
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 4
Thromboxane A2 receptor and Thromboxane-A synthase ligand 3-[(... 3 0
Thromboxane A2 receptor and Thromboxane-A synthase ligand (E)-... 2 0
Thromboxane-A synthase and Thromboxane A2 receptor ligand (E)-... 3 0
Prostaglandin D2 receptor 2 ligand 2-[(8R)-8-[(4-fluorophenyl)... 3 15
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor liga... 20 37
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor liga... 5 2
Dipeptidyl peptidase 4 inhibitor AGN-PC-09QKOM family 5 8
Prostaglandin D2 receptor 2 ligand SureCN2189431 family 7 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 5 1
Pol polyprotein inhibitor Lysine Sulfonamide 6h family 1 1
Prostaglandin D2 receptor 2 ligand 2-[5-fluoro-2-methyl-3-[(4-... 3 5
Pancreatic alpha-amylase and Gastrin/cholecystokinin type B re... 7 1
Prostaglandin D2 receptor 2 ligand 2-[6-fluoro-3-(2-fluoro-4-m... 1 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 4 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 1 1
Thromboxane A2 receptor and Thromboxane-A synthase ligand AGN-... 2 3
Phospholipase A2, membrane associated inhibitor AGN-PC-075RBK ... 1 2
Thromboxane A2 receptor ligand 3-[5-[(4-chlorophenyl)sulfonyla... 1 0
Prostaglandin D2 receptor 2 ligand SureCN2516080 family 1 0
Phospholipase A2, membrane associated inhibitor 4-[3-(2-amino-... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00307952 CHEMBL451553 Bioactive 3-[1-[2-[(4-fluorophenyl)sulfonylamino]ethyl]-2,3-dimethylindol-5-yl]propanoic acid
CFAMM00307965 CHEMBL103924 Bioactive 3-[1-[2-[(4-fluorophenyl)sulfonylamino]ethyl]-3-(pyridin-4-ylmethyl)indol-5-yl]propanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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