CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14407
Family Name Renin inhibitor 2-hydroxy-3-[[(4S,7S)-5-hydroxy-2,8-dimethyl-7-[[(2R)-2-methylbutyl]carbamoyl]nonan-4-yl]carbamoyl]-4-oxo-5-phenylpentanoic acid family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00428346 Functional Category Bioactive
Superfamily Cathepsin F and Cruzipain Inhibitor WRR-99 Superfamily
Class Class 1842

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 7 54
ATP-sensitive inward rectifier potassium channel 10 Ligand Nat... 3 233
Bacterial outer membrane Inhibitor Polymyxin B Family 17 181
Integrin alpha-V and Integrin beta-3 Inhibitor C[rgd-(s)-alpha... 19 95
Renin Inhibitor CP-80794 Family 16 112
Neuromedin-K receptor Ligand Senktide Family 15 22
Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131
Beta-secretase 1 Inhibitor MMI-175 Family 30 137
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Beta-secretase 1 Inhibitor Glu-leu-asp-leu-(choh-ch2)-ala-ala-... 15 11
Calcitonin gene-related peptide type 1 receptor Ligand Fvptdvg... 8 8
Histone deacetylase 1 and Histone deacetylase 4 Inhibitor Azum... 3 10
Integrin alpha-V Inhibitor C[rgdf-(3s)-carboxymorpholine] Family 10 2
Caspase-4 and Cathepsin D Inhibitor Grassystatin A Family 24 6
Mu-type opioid receptor and Nociceptin receptor Ligand Nocicep... 35 5
Serine/threonine protein phosphatase PP1-alpha 1 catalytic sub... 10 0
Renin inhibitor (2S,4S,5S)-N-butyl-6-cyclohexyl-4-hydroxy-5-[[... 12 1
Renin inhibitor tert-butyl N-[1-[[(3S,6S,7R)-6-(cyclohexylmeth... 14 1
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 5 3
Pol polyprotein inhibitor Diol-Based HIV-1 protease inhibitor ... 1 0
Ribonucleoside-diphosphate reductase large subunit and Ribonuc... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00428346 CHEMBL26486 Bioactive 2-hydroxy-3-[[(4S,7S)-5-hydroxy-2,8-dimethyl-7-[[(2R)-2-methylbutyl]carbamoyl]nonan-4-yl]carbamoyl]-4-oxo-5-phenylpentanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27668 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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