CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14418
Family Name Renin inhibitor AGN-PC-002JXB family
No. of Seeds 14 No. of Other Members 0
Family Centroid CFAMM00428422 Functional Category Bioactive
Superfamily Renin and Integrin beta-3 Binder Superfamily
Class Class 195

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
Renin Inhibitor Sul-pro-phe-n-mehis-lva-ile-amp Family 47 54
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Pol polyprotein inhibitor (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5... 2 0
Cholecystokinin receptor type A ligand 6-[2-[2-(cyclohexylmeth... 2 6
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (2... 16 5
Growth hormone secretagogue receptor type 1 ligand SureCN36660... 4 14
Renin inhibitor AGN-PC-073MLF family 7 6
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (3... 1 1


External ID

Functional Category

Molecule Name

CFAMM00428425 CHEMBL305692 Bioactive 4-[[1-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-[[2-[8-(2-methylpropyl)-6-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-3-pyridin-3-ylpropanoyl]amino]-5-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]butanoic acid
CFAMM00428418 CHEMBL77107 Bioactive AGN-PC-002JXA
CFAMM00428424 CHEMBL74564 Bioactive AGN-PC-074IQ0
CFAMM00428417 CHEMBL413031 Bioactive AGN-PC-002JX4
CFAMM00428423 CHEMBL430619 Bioactive AGN-PC-002JX3
CFAMM00428416 CHEMBL74310 Bioactive AGN-PC-002JX8
CFAMM00428422 CHEMBL265486 Bioactive AGN-PC-002JXB
CFAMM00428415 CHEMBL41567 Bioactive AGN-PC-073ML0
CFAMM00428421 CHEMBL307389 Bioactive 2-[[3-(aminomethyl)phenyl]methylamino]-N-[(2S,3S)-1-cyclohexyl-3-hydroxy-5-oxo-5-[[2-(8-propyl-6-pyridin-3-yl-[1,2,4]triazolo[4,3-a]pyrazin-3-yl)-3-pyridin-3-ylpropanoyl]amino]pentan-2-yl]-4-methylpentanamide
CFAMM00428414 CHEMBL307911 Bioactive AGN-PC-074IPY
CFAMM00428420 CHEMBL424423 Bioactive (2S)-2-amino-6-[[1-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-[[2-[8-(2-methylpropyl)-6-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-3-pyridin-3-ylpropanoyl]amino]-5-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]hexanoic acid
CFAMM00428413 CHEMBL307912 Bioactive AGN-PC-074IPZ
CFAMM00428426 CHEMBL76697 Bioactive AGN-PC-002JX6
CFAMM00428419 CHEMBL405700 Bioactive AGN-PC-002JX9

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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