CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14420
Family Name Gamma-aminobutyric acid receptor subunit pi and Gamma-aminobutyric acid receptor subunit gamma-3 ligand 3-(7-fluoro-1,3-benzoxazol-2-yl)-1,3a,4,5,6,7,8,8a-octahydrocyclohepta[d]imidazol-2-one family
No. of Seeds 5 No. of Other Members 2
Family Centroid CFAMM00428432 Functional Category Bioactive
Superfamily Neuropeptide Y receptor type 5 and 5-hydroxytryptamine receptor 6 Binder Superfamily
Class Class 1670

Cousin Family NamesSeedsMembers
Vascular endothelial growth factor receptor 1 and Vascular end... 4 44
Arachidonate 5-lipoxygenase Inhibitor 5-chloro-n-phenylbenzo[d... 3 15
Neutrophil elastase Inhibitor Cbz-val-pro-val-(2-benzoxazole) ... 32 64
5-hydroxytryptamine receptor 3A and Neuronal acetylcholine rec... 2 26
Arachidonate 5-lipoxygenase Inhibitor 5-methyl-n-phenylbenzo[d... 5 13
Arachidonate 5-lipoxygenase Inhibitor 5-methoxy-n-phenylbenzo[... 2 4
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 5 25
5-hydroxytryptamine receptor 3A ligand 2-[(3S)-3-ethylmorpholi... 10 18
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
Cannabinoid receptor 2 ligand [4-(5-tert-butyl-1,3-benzoxazol-... 4 1
Orexin receptor type 1 and Orexin receptor type 2 ligand [(2S,... 2 3
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(1,3-benzoxazol... 3 4
Integrin beta-1 and Integrin alpha-4 inhibitor 4-[[(2S,5S)-5-(... 20 10
Cathepsin S and Cathepsin L1 inhibitor (2S)-2-(1,3-benzoxazol-... 1 9
Cathepsin S and Cathepsin L1 inhibitor SureCN5361439 family 2 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00428435 CHEMBL91702 Bioactive 3-(5-fluoro-1,3-benzoxazol-2-yl)-1,3a,4,5,6,7,8,8a-octahydrocyclohepta[d]imidazol-2-one
CFAMM00428434 CHEMBL91701 Bioactive 3-(6-fluoro-1,3-benzoxazol-2-yl)-1,3a,4,5,6,7,8,8a-octahydrocyclohepta[d]imidazol-2-one
CFAMM00428432 CHEMBL330076 Bioactive 3-(7-fluoro-1,3-benzoxazol-2-yl)-1,3a,4,5,6,7,8,8a-octahydrocyclohepta[d]imidazol-2-one
CFAMM00428431 CHEMBL329804 Bioactive AGN-PC-074P1G
CFAMM00428430 CHEMBL265547 Bioactive AGN-PC-074P5R

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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