CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14427
Family Name Neuropeptide Y receptor type 5 ligand SureCN6835211 family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00428461 Functional Category Bioactive
Superfamily Reverse transcriptase and Amine oxidase [flavin-containing] A Binder Superfamily
Class Class 2257

Cousin Family NamesSeedsMembers
Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family 32 639
Benzodiazepine receptor Ligand Midazolam Family 5 160
Amiloride-sensitive sodium channel subunit alpha Ligand Triamt... 8 98
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Fibroblast growth factor receptor 2 and Fibroblast growth fact... 11 86
Cannabinoid receptor 1 Ligand CP-945598 Family 18 173
HCV NS4B protein Inhibitor Clemizole Family 2 43
Tryptase Inhibitor Babim Family 12 90
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Histamine H3 receptor Ligand SCH79687 Family 11 29
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2,6-di... 13 14
Adenosine receptor A3 Ligand 2,6-bis(4-chlorophenyl)-9h-purine... 4 12
Arachidonate 5-lipoxygenase Inhibitor 2,4,5-triarylimidazole A... 3 16
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Mitogen-activated protein kinase 3 and RAF proto-oncogene seri... 8 5
Adenosine receptor A3 Ligand 2-(5-chloro-1h-benzo[d]imidazol-2... 7 51
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
Dipeptidyl peptidase 4 Inhibitor (5-phenyl-3h-benzo[d]imidazol... 5 13
Aromatase and Cytochrome P450 26A1 Inhibitor Liarozole Family 4 1
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Glycogen synthase kinase-3 beta Inhibitor CHIR-98023 Family 5 6
Reverse transcriptase Inhibitor PT-304 Family 1 0
Sodium channel protein type 1 subunit alpha and Sodium channel... 10 14
Histamine H4 receptor ligand (2Z)-5-chloro-2-[(1-methylpiperid... 2 8
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 5 0
Transient receptor potential M8 protein ligand 2-[(E)-2-(oxan-... 5 3
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 3
Mitogen-activated protein kinase 14 inhibitor 6-[2-(2,6-difluo... 3 0
Urokinase plasminogen activator surface receptor ligand 3-(1H-... 4 0
Receptor-type tyrosine-protein kinase FLT3 and Aurora kinase A... 2 0
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 6 3
Cholinesterase inhibitor 4-[4,5-diphenyl-1-[7-(1,2,3,4-tetrahy... 2 1
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 5 2
Mitogen-activated protein kinase 10 inhibitor CYCLOPROPYL-{4-[... 2 1
Mitogen-activated protein kinase 14 inhibitor 5-[2-(2,6-dichlo... 1 0
Prostaglandin E synthase inhibitor AGN-PC-00EMT0 family 7 3
Pteridine reductase, putative inhibitor 1-[(3,4-dichlorophenyl... 2 1
Cannabinoid receptor 1 ligand AGN-PC-07CPJ5 family 9 14
Prostaglandin E synthase inhibitor AGN-PC-04SSMB family 6 0
Small conductance calcium-activated potassium channel protein ... 1 0
Niemann-Pick C1 protein and Ras-related protein Rab-9A inhibit... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00428461 CHEMBL266241 Bioactive SureCN6835211

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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