CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14447
Family Name Cytosolic phospholipase A2 inhibitor cPLA2alpha Inhibitor family
No. of Seeds 4 No. of Other Members 4
Family Centroid CFAMM00428566 Functional Category Bioactive
Superfamily Cytosolic phospholipase A2 and Cytosolic phospholipase A2 inhibitor cPLA2alpha Binder Superfamily
Class Class 5045

Cousin Family NamesSeedsMembers
Pol polyprotein inhibitor penicillin deriv. 43 family 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00428566 CHEMBL441326 Bioactive cPLA2alpha Inhibitor
CFAMM00428564 CHEMBL8970 Bioactive N-[[(2S,4R)-1-[2-(2,4-difluorobenzoyl)benzoyl]-4-[2-methylpropyl-[(2-phenylphenyl)methyl]amino]pyrrolidin-2-yl]methyl]-4-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]benzamide
CFAMM00428563 CHEMBL385730 Bioactive N-[[(2S,4R)-1-[2-(2,4-difluorobenzoyl)benzoyl]-4-(triphenyl-$l^{4}-sulfanyl)pyrrolidin-2-yl]methyl]-4-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]benzamide
CFAMM00428568 CHEMBL267258 Bioactive (E)-3-[4-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]phenyl]-N-[[(2S,4R)-1-[2-(4-fluorobenzoyl)benzoyl]-4-[2-methylpropyl-[(2-phenylphenyl)methyl]amino]pyrrolidin-2-yl]methyl]prop-2-enamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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