CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14448
Family Name Platelet-derived growth factor receptor beta and Vascular endothelial growth factor receptor 2 ligand 5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[2-(1,2,4-triazol-1-yl)ethyl]-1H-pyrrole-3-carboxamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00428569 Functional Category Bioactive
Superfamily Receptor-type tyrosine-protein kinase FLT3 inhibitor indoline derivative Sunitinib Superfamily
Class Class 5

Cousin Family NamesSeedsMembers
Receptor-type tyrosine-protein kinase FLT3 inhibitor indoline ... 4 151
5-hydroxytryptamine receptor Ligand Ramosetron Family 10 219
Receptor-type tyrosine-protein kinase FLT3 Inhibitor SU5614 Fa... 4 36
Vascular endothelial growth factor receptor 2 Ligand XL999 Family 11 87
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Acetylcholinesterase and Cholinesterase Inhibitor 3-(2-diethyl... 12 160
RAC-beta serine/threonine-protein kinase and 3-phosphoinositid... 11 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00428569 CHEMBL267293 Bioactive 5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[2-(1,2,4-triazol-1-yl)ethyl]-1H-pyrrole-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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