CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14467
Family Name Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5S)-3-hydroxy-5-[[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamoyl]-7-oxo-1,7-diphenylheptan-2-yl]carbamate family
No. of Seeds 4 No. of Other Members 12
Family Centroid CFAMM00428637 Functional Category Bioactive
Superfamily Pol polyprotein and Disintegrin Binder Superfamily
Class Class 3076

Cousin Family NamesSeedsMembers
Beta-secretase 1 Inhibitor MMI-175 Family 30 137
Plasmepsin-2 Inhibitor PS-222036 Family 12 134
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Plasmepsin-2 Inhibitor KNI-10232 Family 8 36
Cholecystokinin receptor type A Ligand CR-1795 Family 19 41
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5R)-3-hydroxy-6... 40 29
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5R)-3-hydroxy-6... 11 8
Pol polyprotein inhibitor AC1L9R8S family 5 4
Pol polyprotein inhibitor (2R,3R,4R,5R)-3,4-dihydroxy-N-[(2S)-... 22 10
Pol polyprotein inhibitor (2S)-4-benzyl-1-[(2S,4R)-4-benzyl-2-... 10 4
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 4
Pol polyprotein inhibitor (2R)-2-benzyl-5-[(3S,5R)-3-benzyl-5-... 11 5
Pol polyprotein inhibitor 3-[[(3S,5R)-5-benzyl-1-[(2S,4R)-4-be... 4 0
Pol polyprotein inhibitor (2R,4S)-5-[(5R)-3-[(3-aminophenyl)me... 4 2
Pol polyprotein inhibitor AC1LADII family 12 1
Pol polyprotein inhibitor SureCN3530080 family 3 8
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5R)-5-benzyl-3-... 3 0
Pol polyprotein inhibitor L-689,502 family 17 2
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 4 4
Pol polyprotein inhibitor AC1LAMTC family 6 0
Pol polyprotein inhibitor AC1NS2O6 family 3 0
Pol polyprotein inhibitor AC1L9R8I family 1 0
Pol polyprotein inhibitor AC1L9R8M family 4 1
Pol polyprotein inhibitor Enantiomer of AG1284 family 7 1
Pol polyprotein inhibitor (3S,5R)-1-[(2S,4R)-6-amino-4-benzyl-... 1 0
Pol polyprotein inhibitor (2R,3R,4R,5R)-2,5-bis[(2-fluoropheny... 4 0
Pol polyprotein inhibitor (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5... 2 0
Pol polyprotein inhibitor (2R)-5-[(3S,5R)-3,5-dibenzyl-2-oxopy... 3 0
Pol polyprotein inhibitor AC1LADB2 family 1 0
Pol polyprotein inhibitor diarylbutanol deriv. 13 family 1 0
Pol polyprotein inhibitor Tertiary Amide deriv. 56 family 1 0
Pol polyprotein inhibitor (2R,4S)-2-benzyl-5-[2-(tert-butylsul... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00428638 CHEMBL318319 Bioactive tert-butyl N-[(2S,3S,5S)-3-hydroxy-5-[[(1R,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamoyl]-7-oxo-1,7-diphenylheptan-2-yl]carbamate
CFAMM00428644 CHEMBL58043 Bioactive SureCN6468109
CFAMM00428637 CHEMBL268512 Bioactive tert-butyl N-[(2S,3S,5S)-3-hydroxy-5-[[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamoyl]-7-oxo-1,7-diphenylheptan-2-yl]carbamate
CFAMM00428641 CHEMBL58277 Bioactive 2-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-oxopentyl]-N-tert-butylbenzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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