CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14472
Family Name Prothrombin and Cationic trypsin inhibitor (2S)-N-[[4-[(Z)-C-aminocarbonohydrazonoyl]thiophen-2-yl]methyl]-1-[(2R)-2-(methanesulfonamido)-3,3-diphenylpropanoyl]pyrrolidine-2-carboxamide family
No. of Seeds 6 No. of Other Members 3
Family Centroid CFAMM00325508 Functional Category Bioactive
Superfamily Prothrombin and Cationic trypsin Binder Superfamily 2
Class Class 3332

Cousin Family NamesSeedsMembers
Kappa-type opioid receptor Ligand Asimadoline Family 14 54
72 kDa type IV collagenase Inhibitor Batimastat Family 6 52
Prothrombin Inhibitor LB30812 Family 12 36
Prothrombin Inhibitor D-leucyl-n-(4-carbamimidoylbenzyl)-l-pro... 13 44
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-[2-(... 2 2
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Trypsin Inhibitor Benzamidrazone Analogue Family 16 6
Substance-K receptor ligand N-[1-[[(2S)-5-[4-(dimethylsulfamoy... 9 16
Coagulation factor X inhibitor (6S,8aS)-2-benzhydrylsulfonyl-N... 5 5
Plasminogen and Plasma kallikrein inhibitor CHEMBL2016864 family 9 16
Prothrombin inhibitor 2-[[(2R)-1-[(2S)-2-[(4-carbamimidoylthio... 9 4
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 4 2
Type-1 angiotensin II receptor ligand AGN-PC-04X45B family 9 12
Prothrombin inhibitor (2S)-N-[(4-carbamimidoylthiophen-2-yl)me... 12 9
Growth hormone secretagogue receptor type 1 ligand (E)-5-amino... 1 1
Growth hormone secretagogue receptor type 1 ligand SureCN76469... 4 4
Sigma non-opioid intracellular receptor 1 ligand ST50280143 fa... 3 54
Vasopressin V1a receptor and Oxytocin receptor ligand (2S)-N-[... 5 4
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 9 7
Kappa-type opioid receptor and Delta-type opioid receptor liga... 9 0
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 6 6
Prothrombin and Trypsin-1 inhibitor 2-[3-(benzylsulfonylamino)... 2 2
Melanin-concentrating hormone receptor 1 ligand N-methyl-4-(4-... 1 0
Growth hormone secretagogue receptor type 1 ligand (2S)-2,6-di... 2 1
Integrin beta-3 and Integrin alpha-IIb inhibitor (2S)-2-(butyl... 8 6
Prothrombin and Cationic trypsin inhibitor (2S)-3-(5-carbamimi... 2 0
Kappa-type opioid receptor and Delta-type opioid receptor liga... 2 1
Carbonic anhydrase 2 inhibitor AGN-PC-07C00S family 4 1
B2 bradykinin receptor ligand CHEMBL2028837 family 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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