CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14486
Family Name Beta-3 adrenergic receptor and Beta-1 adrenergic receptor ligand SureCN5703914 family
No. of Seeds 14 No. of Other Members 1
Family Centroid CFAMM00111940 Functional Category Bioactive
Superfamily Beta-3 adrenergic receptor and Beta-1 adrenergic receptor Binder Superfamily 3
Class Class 2290

Cousin Family NamesSeedsMembers
Beta adrenergic receptor Ligand Levobunolol Family 6 133
Beta-1 adrenergic receptor Ligand Esmolol Family 5 39
Beta-1 adrenergic receptor Ligand Metoprolol Family 29 90
Sodium channel protein type 5 subunit alpha Ligand Hexylcaine ... 4 94
Beta adrenergic receptor Ligand Dipivefrin Family 3 55
Alpha adrenergic receptor Ligand Bevantolol Family 4 48
Muscarinic acetylcholine receptor Ligand Methantheline Family 6 8
Muscarinic acetylcholine receptor Ligand Flavoxate Family 9 350
Beta-2 adrenergic receptor Ligand Salmeterol Xinafoate Family 9 51
C-C chemokine receptor type 2 Ligand CCX915 Family 3 25
Microsomal triglyceride transfer protein large subunit Inhibit... 3 103
Guanylate cyclase soluble subunit beta-1 Inhibitor Cinaciguat ... 7 50
Tyrosine-protein phosphatase non-receptor type 1 Ligand PNU177... 1 5
cAMP-dependent protein kinase type II-beta regulatory subunit ... 34 81
Peroxisome proliferator-activated receptor gamma and Peroxisom... 2 4
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
Beta-2 adrenergic receptor Ligand Gnf-pf-1694 Family 4 70
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 4 10
Peroxisome proliferator-activated receptor delta and Peroxisom... 20 8
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 6 19
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 2 18
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 2
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 10 8
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 0
Multidrug resistance protein 1 inhibitor 1-[2-[(2R)-3-[4-(2,3-... 2 41
Prostaglandin E2 receptor EP4 subtype ligand 4-[(1S)-1-[[2-(tr... 2 1
Peroxisome proliferator-activated receptor delta and Peroxisom... 13 0
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 15 13
Protein kinase C beta type and Protein kinase C eta type inhib... 1 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 5
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 1 3
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 16 2
Beta-3 adrenergic receptor ligand 5-[[(7S)-7-[[(2R)-2-(3-chlor... 6 3
Beta-3 adrenergic receptor ligand 4-[4-[2-[[(2R)-2-(4-aminophe... 3 0
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 0
5-hydroxytryptamine receptor 1A ligand AGN-PC-074R8E family 2 1
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 4 3
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 2 3
2-[4-(6-methoxy-2-oxochromen-3-yl)phenoxy]acetamide NP (s)-n-(... 7 0
NP 5-hydroxy-4-oxo-2-phenyl-4h-chromen-7-yl 2-((tert-butoxycar... 19 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00428752 CHEMBL269816 Bioactive 2-(2-ethoxyethoxy)-4-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]benzoic acid
CFAMM00428751 CHEMBL409533 Bioactive 4-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-2-(2-methylpropoxy)benzoic acid
CFAMM00428750 CHEMBL453835 Bioactive 4-[4-[(2R)-3-hydroxy-2-[[(2R)-2-hydroxy-2-phenylethyl]amino]propyl]phenyl]-2-propan-2-yloxybenzoic acid
CFAMM00428749 CHEMBL271945 Bioactive 4-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-2-propan-2-yloxybenzoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27525 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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