CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14498
Family Name Prostaglandin G/H synthase 2 inhibitor 2-(4-methylsulfonylphenyl)-4-(thiophen-2-ylmethylsulfanyl)-6-(trifluoromethyl)pyrimidine family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00428786 Functional Category Bioactive
Superfamily Glucosylceramidase and Prostaglandin G/H synthase 2 Binder Superfamily
Class Class 1151

Cousin Family NamesSeedsMembers
Neuropeptide Y receptor type 5 Ligand CGP71683A Family 5 74
Corticotropin-releasing factor receptor 1 Ligand CRA1000 Family 4 39
Hepatocyte growth factor receptor Ligand 3-(phenylsulfonyl)-1h... 17 59
Prostaglandin G/H synthase 2 Inhibitor GW-637185X Family 27 48
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 22
Corticotropin-releasing factor receptor 1 Ligand N-mesityl-6-m... 3 2
Cell division cycle 7-related protein kinase inhibitor AGN-PC-... 6 6
Growth hormone secretagogue receptor type 1 ligand AGN-PC-0760... 4 0
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 7
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 7
Prostaglandin G/H synthase 2 inhibitor 4-N,4-N-diethyl-2-(4-me... 5 1
Prostaglandin G/H synthase 2 inhibitor 6-ethoxy-2-(4-methylsul... 5 1
Focal adhesion kinase 1 and Protein-tyrosine kinase 2-beta inh... 1 1
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00428786 CHEMBL270294 Bioactive 2-(4-methylsulfonylphenyl)-4-(thiophen-2-ylmethylsulfanyl)-6-(trifluoromethyl)pyrimidine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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