CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14502
Family Name C-C chemokine receptor type 2 ligand 2-amino-N-[2-[[(3R)-1-[(3-amino-4-methoxyphenyl)methyl]pyrrolidin-3-yl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00428795 Functional Category Bioactive
Superfamily C-C chemokine receptor type 2 and Collagenase 3 Binder Superfamily
Class Class 3140

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Histamine H3 receptor Ligand A-317920 Family 9 240
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Urotensin-2 receptor Ligand JNJ-28318706 Family 4 227
D(2) dopamine receptor Ligand Epidepride Family 31 66
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
Neutrophil elastase inhibitor (2S)-N-[(3S)-6-benzamido-5,5-dif... 6 10
Trace amine-associated receptor 1 ligand EPPTB family 4 9
Angiotensin-converting enzyme and Angiotensin-converting enzym... 3 13
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 2 3
Melanin-concentrating hormone receptor 1 and Potassium voltage... 3 6
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075X1U ... 2 3
Growth hormone secretagogue receptor type 1 ligand (2R)-N-(1-b... 11 4
C-C chemokine receptor type 2 ligand 2-amino-N-[2-[[(3R)-1-[(4... 2 6
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 10 1
Dipeptidyl peptidase 4 inhibitor SureCN5777647 family 1 0
Nicotinamide phosphoribosyltransferase inhibitor N-(1,3-benzod... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00428795 CHEMBL270435 Bioactive 2-amino-N-[2-[[(3R)-1-[(3-amino-4-methoxyphenyl)methyl]pyrrolidin-3-yl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamide
CFAMM00428796 CHEMBL404269 Bioactive 2-amino-N-[2-[[(3R)-1-[(3-hydroxy-4-methoxyphenyl)methyl]pyrrolidin-3-yl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27511 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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