CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14508
Family Name Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-[[[(2S)-2-carboxy-2-hydroxyethyl]-(2-methylpropyl)carbamoyl]amino]-3-(4-hydroxyphenyl)propanoic acid family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00212347 Functional Category Bioactive
Superfamily Glucan synthesis regulatory protein Inhibitor Caspofungin Superfamily
Class Class 323

Cousin Family NamesSeedsMembers
Vasopressin V2 receptor ligand peptide analog Desmopressin family 111 1472
Oxytocin receptor Ligand Oxytocin Family 30 182
Beta-1 adrenergic receptor Ligand Esmolol Family 5 39
Tyrosine 3-monooxygenase Inhibitor L-tyrosine Family 4 36
Glucan synthesis regulatory protein Inhibitor Caspofungin Family 17 71
Glycoprotein IIb/IIIa receptor Ligand Tirofiban Family 4 173
Growth hormone-releasing hormone receptor ligand polypeptide ... 14 34
Mu-type opioid receptor Ligand Alvimopan Family 32 325
Thymopentin family 20 133
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
Plitidepsin family 15 5
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Neuropeptide Y receptor type 1 Ligand Bibp 3226 Family 43 80
Vasopeptidase Inhibitor Sampatrilat Family 25 9
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 20 35
Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Proto-oncogene tyrosine-protein kinase Src Inhibitor Glu-pro-g... 8 4
Plasmepsin-1 and Plasmepsin-2 Inhibitor PS-777621 Family 11 13
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
Proto-oncogene tyrosine-protein kinase Src Inhibitor Y-c[d-pen... 20 66
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Proto-oncogene tyrosine-protein kinase Src Inhibitor Ac-cys-il... 36 12
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 23 9
Mu-type opioid receptor and Nociceptin receptor Ligand Ac-ryyr... 60 11
C-X-C chemokine receptor type 4 Ligand Cyclo(-d-tyr-l-ala-l-ar... 25 23
Prothrombin Inhibitor Cyclotheonamide E5 Family 3 0
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 49 19
Mu-type opioid receptor Ligand H-tyr-d-ala-aic-asp-val-val-gly... 48 8
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 12 8
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 152 36
Sodium-dependent dopamine transporter Inhibitor Bip-tyr-thr-pr... 8 2
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 48 10
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 95 46
Neprilysin and Angiotensin-converting enzyme inhibitor AGN-PC-... 3 7
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 6 1
Tyrosine--tRNA ligase, cytoplasmic inhibitor (2S)-2-[[(2S)-2-a... 5 2
Pol polyprotein inhibitor AC1LADQG family 7 1
Angiotensin-converting enzyme 2 and Neprilysin inhibitor (2S)-... 6 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2R)-3-[4-(2-me... 18 1
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 1 0
N-acetylated-alpha-linked acidic dipeptidase 2 inhibitor (2S)-... 1 5
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 2
Sodium-dependent dopamine transporter inhibitor AC1MIIGH family 2 0
C-C chemokine receptor type 3 ligand SureCN3932025 family 1 1
N-formyl-2-(4-hydroxyphenyl)acetamide NP Agn-pc-04a0ox Family 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48680 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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