CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14526
Family Name Serine/threonine-protein kinase Chk1 and Wee1-like protein kinase inhibitor AGN-PC-03ILAS family
No. of Seeds 3 No. of Other Members 12
Family Centroid CFAMM00428930 Functional Category Bioactive
Superfamily Bile acid receptor and Heparanase Binder Superfamily
Class Class 4064

Cousin Family NamesSeedsMembers
Vascular endothelial growth factor receptor 2 Ligand Isoindoli... 11 36
Serine/threonine-protein kinase Chk1 and Wee1-like protein kin... 2 101
High affinity nerve growth factor receptor and Mitogen-activat... 2 7
Protein kinase C alpha type and Protein kinase C delta type in... 4 37
Wee1-like protein kinase and Serine/threonine-protein kinase C... 3 51
Wee1-like protein kinase and Serine/threonine-protein kinase C... 8 0
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 6 8
Arachidonate 5-lipoxygenase inhibitor AGN-PC-071TED family 9 12
Vascular endothelial growth factor receptor 2 ligand SureCN235... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00428930 CHEMBL272479 Bioactive AGN-PC-03ILAS
CFAMM00428922 CHEMBL271071 Bioactive 4-(2-chlorophenyl)-9-hydroxy-8-(3-pyrrolidin-1-ylpropoxy)-6H-pyrrolo[3,4-c]carbazole-1,3-dione
CFAMM00428934 CHEMBL410261 Bioactive SureCN5829060

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27419 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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