CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14537
Family Name Protein kinase C delta type and Protein kinase C beta type inhibitor (2s,5s)-5-(hydroxymethyl)-1-methyl-9-octyl-2-(propan-2-yl)-1,2,4,5,6,8-hexahydro-3h-[1,4]diazonino[7,6,5-cd]indol-3-one family
No. of Seeds 4 No. of Other Members 4
Family Centroid CFAMM00428969 Functional Category Bioactive
Superfamily Protein kinase C eta type and Protein kinase C beta type Binder Superfamily
Class Class 643

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 4 171
D(1A) dopamine receptor ligand ergot alkaloid Methylergonovine... 22 170
Gastrin/cholecystokinin type B receptor ligand peptide Pentaga... 26 1171
Somatostatin receptor type 2 ligand octapeptide Octreotide Family 27 172
Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family 8 328
Bacterial outer membrane Inhibitor Daptomycin Family 6 50
Fibroblast growth factor receptor 1 and Aurora kinase B Inhibi... 4 51
Substance-P receptor Ligand GSK424887 Family 8 184
Growth hormone receptor Ligand EP-51216 Family 34 390
Gastrin/cholecystokinin type B receptor Ligand PD136450 Family 53 117
Lethal factor Inhibitor GM6001 Family 50 435
Somatostatin receptor type 2 Ligand L-054852 Family 13 88
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[n... 12 10
Angiotensin-converting enzyme and Endothelin-converting enzyme... 2 10
Endothelin B receptor Ligand IRL-2500 Family 34 87
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 17 28
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 3 0
Caspase-1 inhibitor (3S)-3-[[(2S)-4-[2-(1,2-dimethylindol-3-yl... 3 4
Caspase-1 inhibitor (3S)-4-oxo-3-[[(2S)-4-oxo-2-propan-2-yl-4-... 3 0
Somatostatin receptor type 2 ligand tert-butyl (2S)-6-amino-2-... 1 2
Growth hormone-releasing hormone receptor ligand ethyl (1S)-1'... 3 2
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 3 0
Somatostatin receptor type 4 ligand methyl 5-(diaminomethylide... 2 34
Interstitial collagenase and Matrilysin inhibitor (2S,3R)-N,2-... 3 1
Neuropeptide Y receptor type 5 ligand 2-indol-1-yl-N-[4-[(prop... 7 6
Prothrombin and Tissue-type plasminogen activator inhibitor 2-... 4 5
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 1 4
Endothelin B receptor and Endothelin-1 receptor ligand 2-[[(2R... 17 10
Neprilysin and Endothelin-converting enzyme 1 inhibitor (2S)-2... 5 0
Endothelin-1 receptor and Endothelin B receptor ligand 2-[[(2R... 5 3
Angiotensin-converting enzyme inhibitor AC1L1IZN family 2 2
Interstitial collagenase and Stromelysin-1 inhibitor CHEMBL887... 1 0
Neprilysin inhibitor AGN-PC-073PUZ family 1 0
5-(carbamoylamino)pentanoate NP ZINC12297125 Family 8 0
NP Agn-pc-099dao Family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00428963 CHEMBL271403 Bioactive CHEMBL271403
CFAMM00428969 CHEMBL285801 Bioactive (2s,5s)-5-(hydroxymethyl)-1-methyl-9-octyl-2-(propan-2-yl)-1,2,4,5,6,8-hexahydro-3h-[1,4]diazonino[7,6,5-cd]indol-3-one
CFAMM00428962 CHEMBL399981 Bioactive 99414-61-6
CFAMM00428968 CHEMBL417692 Bioactive Teleocidin B

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27261 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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